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Step 1 Pharmacology > Drug Reactions > Flashcards

Drug Reactions Flashcards

1
Q

Coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids

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2
Q

Cutaneous flushing

A

Vancomycin, Adenosine, Niacin, CCBs [VANC]

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3
Q

Dilated cardiomyopathy

A

Doxorubicin, daunorubicin

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4
Q

Torsades de pointes

A

Class III and class IA antiarrhythmics, macrolide antibiotics, antipsychotics, TCAs

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5
Q

Adrenocortical insufficiency

A

HPA suppression secondary to steroid withdrawal

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6
Q

hot flashes

A

tamoxifen, clomiphene

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7
Q

hyperglycemia

A

tacrolimus, protease inhibitors, niacin, HCTZ, beta-blockers, corticosteroids [taking pills necessitates having blood check]

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8
Q

hypothyroidism

A

lithium, amiodarone, sulfonamides

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9
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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10
Q

diarrhea

A

metformin, erythromycin, colchicine, orlistat, acarbose [might excite colon on accident]

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11
Q

focal to massive hepatic necrosis

A

halothane, amanita phalloides (death cap), valproate, acetaminophen [Liver HAVAc

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12
Q

Hepatitis

A

INH

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13
Q

Pancreatitis

A

Didanosine, corticosteroids, alcohol, valproate, azathioprine, diuretics [drugs causing a violent abdominal distress]

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14
Q

pseudomembrnaous colitis

A

clindamycin, ampicillin, cephalosporins

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15
Q

agranulocytosis

A

dapsone, clozapine, carbamaepine, colchicine, methimazole, propylthiouracil [drugs CCCrush myeloblasts and promyelocytes]

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16
Q

aplastic anemia

A

carbamazepine, methimazole, NSAIDs, benzene, chloramphenicol, propylthiouracil [can’t make new blood cells properly]

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17
Q

direct coombs-positive hemolytic anemia

A

methyldopa, penicillin

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18
Q

gray baby syndrome

A

chloramphenicol

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19
Q

hemolysis in G6PD deficiency

A

INH, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin [hemolysis IS D PAIN]

20
Q

megaloblastic anemia

A

Phenytoin, Methotrexate, Sulfa drugs

21
Q

Thrombocytopenia

A

Heparin, cimetidine

22
Q

Thrombotic complications

A

OCPs

23
Q

Fat redistribution

A

Protease inhibitors, glucocorticoids [Fat PiG]

24
Q

gingival hyperplasia

A

phenytoin, verapamil, cyclosporine, nifedipine

25
Q

hyperuricemia

A

pyrazinamide, thiazides, furosemide, niacin, cyclosporine (painful tophi and feet need care)

26
Q

myopathy

A

fibrates, niacin, colchicine, hydroxychloroquine, interferon-alpha, penicillamine, statins, glucocorticoids

27
Q

osteoporosis

A

corticosteroids, heparin

28
Q

photosensitivity

A

sulfonamides, amiodarone, tetracycliens, 5-FU

29
Q

Stevens-Johnsons

A

Anti-epileptics, allopurinol, sulfa drugs, penicillin

30
Q

SLE-like syndrome

A

Sulfa drugs, Hydralazine, INH, procainamide, phenytoin, etanercept [having lupus is SHIPP-E]

31
Q

Teeth discoloration

A

Tetracyclines

32
Q

Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

33
Q

Cinchonism

A

quinidine, quinine

34
Q

parkinson-like syndrome

A

antipsychotics, reserpine, metoclopramide

35
Q

seizures

A

INH (B6 deficiency), bupropion, imipenem/cilastatin, tramadol, enflurane, metoclopramide

36
Q

tardive dyskinesia

A

antipsychotics, metoclopramide

37
Q

diabets insipidus

A

lithium, demeclocycline

38
Q

fanconi syndrome

A

expired tetracycline

39
Q

hemorrhagic cystitis

A

cylophosphamide, ifosfamide (prevent with coadministering mesna)

40
Q

interstitial nephritis

A

methicillin, NSAIDs, furosemide

41
Q

SIADH

A

carbamazepine, cyclophosphamide, SSRIs [can’t concentrate serum sodium]

42
Q

dry cough

A

ACEIs

43
Q

Pulm. fibrosis

A

bleomycin, amiodarone, busulfan, methotrexate [breathing air badly from medications]

44
Q

disulfiram-like reaction

A

flagyl, certain cephalosporins, griseofulvin, procarbazine, 1st gen sulfonylurea

45
Q

nephrotoxicity/ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin

46
Q

antimuscarinic

A

atropine, TCAs, h1-blockers, antipsychotics

47
Q

sulfa drugs

A

probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamide antibiotics, sulfasalazine, sulfonylureas [Popular FACTSSS]

Step 1 Pharmacology (17 decks)

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