Surgery Of Adrenal Glands Flashcards

1
Q

What secretes Catecholamines?

A

Medulla

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2
Q

What is the Catecholamine secreted by the Medulla

A

Adrenaline

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3
Q

What secretes Aldosterone

A

Zone Glomerulosa

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4
Q

What does Aldosterone do

A

Regulates sodium-potassium homeostasis, mainly sodium retention and potassium excretion

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5
Q

What are the regulators of Aldosterone?

A

Renin-angiotensin system and serum potassium concentration

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6
Q

What cells produce Renin

A

Juxtaglomerular cells

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7
Q

Where is Cortisol secreted

A

Zona Fasciculata

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8
Q

What is Cortisol secretion regulated by?

A

ACTH from the anterior pituitary

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9
Q

An Excess of Cortisol, leads to what syndrome?

A

Cushing Syndrome

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10
Q

Catecholamine pathology leads to what?

A

Pheochromocytoma

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11
Q

Aldosterone excess leads to what?

A

Conn’s syndrome (Primary hyperaldosteronism)

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12
Q

Most common cause of Conn’s?

A

Adenocortical adenoma

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13
Q

Most common cause of Conn’s?

A

Adenocortical adenoma

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14
Q

Imaging modalities of Conn’s

A

Adrenal CT if greater than 1cm, also an MRI should a CT be contraindicated

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15
Q

Imaging modality of Conn’s should it be smaller than 1cm?

A

PET radiotracer

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16
Q

What investigation do we do for Conn other than imaging?

A

Adrenal venous sampling (AVS)

17
Q

Treatment of choice for Conn’s?

A

Laparoscopic Adrenalectomy

18
Q

Most common cause of Cushing?

A

Pituitary adenoma

19
Q

Investigation of Cushing?

A

If ACTH low, we do a CT or MRI to assess the adrenal glands

20
Q

What is Congenital Adrenal Hyperplasia

A

The inadequate production of cortisol and or aldosterone

21
Q

Investigation of Adrenal Hyperplasia reveals what as a diagnostic sign

A

Serum 17 hydroxyprogesterone >1000

22
Q

What is Addisonian crisis

A

An acute adrenal insufficiency

23
Q

What is Waterhouse-Frederichsen syndrome

A

A bilateral adrenal infarction associated with meningococcal sepsis. Rapidly fatal unless immediately treated

24
Q

Addisonian crisis treatment?

A

Immediate, Hydrocortisone IV and Saline

25
Q

Pheochromocytoma is a tumor where?

A

Adrenal medulla