Sulfonamide DI Flashcards
1
Q
Sulfonamide
A
SMX/TMP (Bactrim)
2
Q
Sulfonamide MoA
A
Inhibits sequential steps in the formation of tetrahydrofolate in bacteria which inhibits purine synthesis
3
Q
Are sulfonamides bacteriostatic or bacteriocidal?
A
Bacteriostatic
4
Q
Bactrim spectrum of activity
A
++ against gram-positive aerobes, MRSA, MSSA
++/+++ against gram-negative aerobes
5
Q
Bactrim side effects
A
GI intolerance, rash, anemia, crystalluria, neutropenia
6
Q
Bactrim is the drug of choice for…
A
…pneumocystis carinii pneumonia