Sulfonamide DI Flashcards

1
Q

Sulfonamide

A

SMX/TMP (Bactrim)

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2
Q

Sulfonamide MoA

A

Inhibits sequential steps in the formation of tetrahydrofolate in bacteria which inhibits purine synthesis

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3
Q

Are sulfonamides bacteriostatic or bacteriocidal?

A

Bacteriostatic

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4
Q

Bactrim spectrum of activity

A

++ against gram-positive aerobes, MRSA, MSSA

++/+++ against gram-negative aerobes

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5
Q

Bactrim side effects

A

GI intolerance, rash, anemia, crystalluria, neutropenia

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6
Q

Bactrim is the drug of choice for…

A

…pneumocystis carinii pneumonia

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