Lincosamides DI Flashcards
1
Q
Lincosamide
A
Clindamycin
2
Q
Lincosamide MoA
A
Same as macrolide MoA (reversibly bind to 50S ribosomal subunit to inhibit bacterial protein synthesis)
3
Q
Lincosamide spectrum of activity
A
+++ against gram-positive aerobes
4
Q
Lincosamide side effects
A
GI intolerance, pseudomembranous colitis
5
Q
Are lincosamides bacteriostatic or bactericidal?
A
Bacteriostatic