Lincosamides DI Flashcards

1
Q

Lincosamide

A

Clindamycin

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2
Q

Lincosamide MoA

A

Same as macrolide MoA (reversibly bind to 50S ribosomal subunit to inhibit bacterial protein synthesis)

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3
Q

Lincosamide spectrum of activity

A

+++ against gram-positive aerobes

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4
Q

Lincosamide side effects

A

GI intolerance, pseudomembranous colitis

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5
Q

Are lincosamides bacteriostatic or bactericidal?

A

Bacteriostatic

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