Lipopeptide DI Flashcards

1
Q

Lipopeptide

A

Daptomycin

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2
Q

Lipopeptide MoA

A

Irreversibly binds to the bacterial cell membrane, rapidly depolarizes it, and causes cell death

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3
Q

Are lipopeptides bacteriostatic or bactericidal?

A

Bactericidal

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4
Q

Daptomycin spectrum of activity

A

+++ against gram-positive anaerobes, MRSA, MSSA, and enterococcus

+/++ activity against gram-negative anaerobes

No activity against gram-negative aerobes

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5
Q

Daptomycin isn’t indicated for what?

A

Pneumonia

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6
Q

Daptomycin monitoring

A

Muscle pain or weakness, CPK levels

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