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phm 603- id part 1 > Penicillins DI > Flashcards

Penicillins DI Flashcards

1
Q

Natural penicillins

A

Pen G and Pen V

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2
Q

Aminopenicillin

A

Ampicillin

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3
Q

Penicillinase resistant penicillin

A

Nafcillin, dicloxacillin

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4
Q

Ureido-penicillin

A

Piperacillin

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5
Q

Beta-lactam/beta-lactamase inhibitor combination PCNs

A

Amox/clav, ampicillin/sulbactam, ticarcillin/clav, pip/tazo

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6
Q

PCN MoA

A

Bind to transpeptidase enzymes in the bacterial cell and disrupt cell wall formation

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7
Q

Are PCNs bacteriostatic or bactericidal?

A

Bactericidal

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8
Q

Pen G snd Pen V spectrum of activity

A

+++ against gram-positive organisms and enterococcus

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9
Q

Pen G and Pen V side effects

A

Hypersensitivity, rash, seizures, CDAD

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10
Q

Ampicillin spectrum of activity

A

+++ against gram-positive organisms and enterococcus

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11
Q

Ampicillin side effect

A

Mononucleosis rash

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12
Q

Nafcillin and dicloxacillin spectrum of activity

A

+++ against gram-positive aerobes and MSSA

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13
Q

Nafcillin and dicloxacillin side effects

A

Neutropenia, interstitial nephritis, thrombophlebitis

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14
Q

Piperacillin spectrum of activity

A

+++ against pseudomonas

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15
Q

Piperacillin side effects

A

Neutropenia, diarrhea, headache

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16
Q

Beta-lactam-beta-lactamase inhibitor combination spectrum of activity

A

+++ against gram-negative AEROBES

17
Q

Beta-lactam-beta-lactamase inhibitor combination spectrum side effect

A

Diarrhea

18
Q

PCNs may have cross-reactivity with what two other ABX classes?

A

Carbapenems and cephalosporins

phm 603- id part 1 (22 decks)

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