Cephalosporins DI Flashcards
3rd generation cephalosporins
Ceftazidime, ceftriaxone
4th generation cephalosporin
Cefepime
Cephalosporins MoA
Same as PCNs! Bind to transpeptidase enzymes in the bacterial cell and disrupt cell wall formation
Ceftazidime and cefepime spectrum of activity
+++ against pseudomonas
Ceftazidime side effects
Increased LFTs, neutropenia
Cefepime side effects
Similar to PCNs
Cephalosporins for proteus mirabilis
Cephalexin, cefazolin
1st generation cephalosporins
Cephalexin, cefazolin
Cephalosporin for E. coli
Cefazolin
Cephalosporin for Klebsiella
Cefazolin
Alternate treatment for E. coli
Gentamicin
Cephalosporin for H. influenzae
Cefoxitin, cefaclor, cefotetan
2nd generation cephalosporins
Cefoxitin, cefaclor, cefotetan
Cephalosporin for Moraxella
Ceftriaxone
Cephalosporin for serratia marcescens
Ceftriaxone and cefepime