Substance Abuse Flashcards
___ is the most common drug of abuse
alcohol
Alcohol
- CNS depressant
- teratogen (fetal alcohol syndrome)
- affects judgement, concentration, coordination
- 25% of auto accidents
Dental Aspects - Alcohol
- impaired informed consent
- erratic appointments
- aggressive behavior
- anemia/thrombocytopenia
- drug interactions
- altered drug metabolism (especially drugs that are metabolized by the liver)
- avoid general anesthesia
Aspirin and NSAIDs should be avoided for patients with __
alcohol dependency
Poor wound healing, sialosis, leukoplakia, and squamous cell cacinoma are characteristic of ___
alcohol dependency
Amphetamines
- euphoriant
- counters fatigue
- weight loss
Elevated BP, hyperpyrexia, insomnia, anorexia, hallucinations/paranoia, hyposalivation, rampant caries, and bruxism are characteristic of patients with __
amphetamine dependency
Barbiturates
- sedative-hypnotics
- treaty anxiety and insomnia (not commonly used today)
- cause respiratory depression, bradycardia, impaired cognition
- narrow therapeutic index
- often mixed with other recreational drug (heroin)
Therapeutic Index
How much of the drug is required to get the desired affect from the drug?
Benzodiazopenes
- anxiolytics
- psychological effects (relatively) less severe
- rapid physical dependence
- insomnia, paradoxical anxiety (makes you more anxious instead of less), anorexia, occasional psychotic episodes
Cocaine
- common drug of abuse
- profound, immediate CNS effects
* *hyperstimulation
* *diminished fatigue
* *diminished appetite
* *feeling of well-being
Cocaine mimics __
adrenaline
1 dilated pupils
- peripheral constriction
- hyperpyrexia
- tachycardia
- hypertension
Paranoia, visual hallucinations, formication (itchy sensation), cardiovascular effects, respiratory depression, ischemic necrosis (perforated septum and hard palate) is characteristic of __
cocaine
What are the withdrawl symptoms of cocaine?
- depression
- sleep craving
- fatigue
- recurrence of craving
Cocaine - Dental Aspects
- blood-borne infections
- xerostomia
- bruxism
- dental erosion
- NO EPI for 2 hours after last use
- best to treat 6 hours after last use
__ is the second most commonly abused substance
marijuana
Marijuana
- influence pleasure, memory, thought, concentration, sensory/time perception
- impaired attention, memory, learning
- 50-70% more carcinogens that tobacco**
4 impaired immune function, increased risk of MI, respiratory infection, fetal neurological maldevelopment - xerostomia, increased appetite, oral leukoplakia
Opioid analgesics
- morphine
2. heroin
Synthetic opioids
- methadone
2. codeine
Clinical Aspects - Opiates and Opioids
- analgesia
- respiratory depression
- nausea
- decreased GI motility**
- sedation
- addiction
- CNS depression/sleepiness
- euphoria
- constricted pupils
- impaired mental function
Weight loss, self-neglect, needle marks, drug tolerance is characteristic of __
analgesic and opioid addicts
Dental Aspects - Opiates and Opioids
- significant dental neglect
- cariogenic diet
- pain control is difficult
Ischemic necrosis (hole in septum and hard palate)
cocaine
altered drug metabolism (especially drugs that are metabolized by liver)
alcohol
Elevated BP
amphetamine
Hyperpyrexia
amphetamine
Insomnia
amphetamine, Benzodiazopenes
Anorexia
amphetamine
Hallucinations/paranoia
amphetamine
Hyposalivation
amphetamine
Rampant caries
amphetamine
Bruxism
amphetamine
Sedative-hynotics
Barbiturates
treats anxiety and insomnia
Barbiturates
respiratory depression, bradycardia, impaired cognition
Barbiturates
narrow therapeutic index
Barbiturates
often mixed with heroin
Barbiturates
Anxiolytics
Benzodiazopenes
psychological effects LESS severe
Benzodiazopenes
paradoxical anxiety
Benzodiazopenes
anorexia
Benzodiazopenes
psychotic episodes
Benzodiazopenes
Paranoia/visual hallucination
cocaine
itchy sensation
cocaine
cardiovascular effects
cocaine
respiratory depression
cocaine
influences pleasure, memory, thought, concentration, sensory/time perception
marijuana
50-70% more carcinogens than tobacco
marijuana
impaired immune funtion
marijuana
increased risk of MI
mairjuana
respiratory infection
marijuana
fetal neurological mal-development
marijuana
decreased GI motility
opiates and opioids
significant dental neglect
opiates and opioids
cariogenic diet
opiates and opioids