Materials and Drugs Flashcards

1
Q

Chlorhexidine Allergy

A
  1. rare allergy
  2. antiseptic/disinfectant
  3. treat like latex allergy
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2
Q

Metal allergies

A
  1. gold alloys: rare
  2. mercury amalgam: silver, tin, copper, zinc–>Lichenoid rxn
  3. Nickel: nickel titanium orthodontic wire, jewelry
  4. titanium: rare
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3
Q

Dental cement allergies are rare/common

A

rare

  1. zinc phosphate
  2. zinc oxide and eugenol
  3. polycaroxylate
  4. glass ionomer
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4
Q

Bis-phenol A allergy in dental sealants and composites

A
  1. in vitro estrogenic activity
  2. obesity, diabetes, cardiovascular disease, polycystic ovaries, low sperm count
  3. SMALL amount of leaching compared to plastic bottles and can liners
  4. NO basis for dental concern
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5
Q

Zinc in Polygrip and Fixodent

A
  1. absorption potentially causes copper deficiency
  2. can lead to myelopathy and polyneuropathy WHEN NOT USED IN ACCORDING TO MANUFACTURER’S DIRECTIONS
  3. Sln - reformulate products to “zinc free”
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6
Q

__ is the level of water fluoridation in WI

A

0.7 ppm

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7
Q

Fluoridation

A

No relationship to

  1. bladder cancer or osteosarcoma
  2. bone strength, mineral density, bone fracture
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8
Q

Mercury

A

high levels are neurotoxic and nephrotoxic

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9
Q

__ mercury poisoning is the most common

A

organic

ex: industrial pollution gets into fish

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10
Q

Inorganic mercury salt poisoning is rare/common

A

rare

  1. acrodynia: exfoliation, hypersalivation, muscular, hypotonia, peripheral edema
  2. GI ulceration, necrosis
  3. renal failure
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11
Q

Metallic mercury

A
  1. neurotoxic and nephrotic
  2. mining
  3. santeria - Carribean religious practice
  4. accidents
  5. suicide
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12
Q

Acute Mercury Toxicity

A

rare

  1. penumonitis
  2. CNS symptoms (tremors, excitability)
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13
Q

Chronic mercury toxicity

A

rare

  1. tremor
  2. incoordination
  3. polyneuropathies
  4. senility
  5. anorexia
  6. weight loss
  7. accelerated periodontal disease, gingival pigmentation
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14
Q

Mercury Hygiene

A
  1. no hand trituration of amalgam
  2. no carpeting in dental operatories
  3. no handling of amalgam scraps
  4. common sense
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15
Q

Amalgam emits mercury vapor when __

A
  1. chewing
  2. eating
  3. tooth brushing
  4. drinking hot liquids
  5. H2O2
  6. amalgam removal
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16
Q

__ (states) have statuatory informed consent for amalgam

A
  1. CA
  2. CT
  3. ME
  4. VT
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17
Q

Amalgam is illegal in __ (country)

A

Scandinavia

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18
Q

Mercury disposal

A
  1. amalgam separators (95% effective)

2. amalgam disposal

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19
Q

Water tx plants are __ (percent) effective in removing mercury

A

90%

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20
Q

OTC tooth-whitening

A
  1. trays (10% carbamide peroxide containing 3% H2O2)
  2. paint-on (3-10% H2O2(
  3. strips (6% H2O2)
21
Q

Dentrifices

A
  1. contact dermatitis
  2. contact mucositis
    * *cinnamon flavored products
    * *plasma cell gingivitis
    * *tartar-control dentrifices with cinnamon or pyrophosphates
  3. orofacial granulomatosis
    * *zirconium
22
Q

Pediatric patients need higher/lower drug dosages than adults

23
Q

Most drug allergies/hypersensitivities are __ (antibody) mediated

24
Q

Drug Allergy Diagnosis

A
  1. clinical: rash or anaphylaxis

2. lab: skin testing

25
Drug Allergy Tx
1. discontinue drug | 2. pt education
26
Adverse effects with IV anesthetics
anaphylaxis
27
Adverse effects with analgesics
1. aspirin: platelet dysfunction | 2. acetaminophen: liver dysfunction
28
Adverse effects with anti-convulsants
1. usually skin eruptions | 2. potentially fatal
29
Iodinated IV Contrast Media
1. 5-8% of patients 2. 1% of IgE-mediated urticaria/nausea/vomiting 3. 0.1% anaphylaxis
30
How to avoid negative drug interactions
1. avoid polypharmacy 2. only use drugs you are familiar with 3. get a consult with an MD 4. be VERY careful * *general anesthesia * *geriatric patients * *poor historians
31
Anticholinergic drugs cause __
hyposalivation
32
Chemotherapy drugs cause __
oral ulcers
33
Corticosteroids and antibiotics cause __
candidiasis
34
Phenytoin, cyclosporin, and calcium channel blockers cause __
gingival hyperplasia
35
Contact allergy to cosmetics or food causes __
chelitis
36
Halitosis is caused by __
1. multiple drugs | 2. xerostomia
37
Movement disorders can be caused by __
anti-psychotics
38
Neoplasms can be caused by __
long-term corticosteroids
39
Stomatodynia/dysesthesia can be caused by __
HTN medications
40
Pigmentation can be caused by __
1. bismuth 2. chlorhexidine 3. amalgam 4. metal crown copings 5. heavy metals 6. anti-malarials 7. anti-psychotics 8. anti-convulsants 9. antibiotics
41
Anticholinergics can cause __
sialorrhea
42
Gingival enlargement can be caused by __
1. phenytoin 2. cyclosporine 3. calcium channel blockers
43
Swelling in the lips/floor of mouth can be caused by __
Type 1 hypersensitivity reactions
44
Angioedema can be caused by __
1. penicillins 2. ACE inhibitors 3. aspirin
45
Hypogeusia
loss of taste acuity
46
Dysgeusia
distortion of taste function
47
Ulceration
1. misapplication of products: aspirin, tooth-ache drops, K+ tabs, H2O2 2. chemotherapy drugs - MTX, 5-FU 3. NSAIDs, beta blockers, bisphosphonates
48
Xerostomia can be caused by __
1. smoking 2. alcohol 3. drugs