Structure

Question 1

What are the layers of the epidermis?

Answer 1

Keratin
Granular
Prickle cell
Basal cell

Question 2

What type of tissue does the Dermis consist of?

Answer 2

Connective

Question 3

What type of tissue does the Epidermis consist of?

Answer 3

Stratified Cellular Epithelium

Question 4

What are the appendages of the skin?

Answer 4

Nails
hair
Glands
Mucosae

Question 5

What is epidermal turnover regulated by?

Answer 5

Growth factors
Cell death
Hormones

Question 6

When is epidermal turnover regulations lost?

Answer 6

Psoriasis and cancer

Question 7

Describe the basal layer

Answer 7

One cell thick, small cuboidal.
Highly metabolically active
Lots of intermediate filaments, keratin

Question 8

Where do keratinocytes migrate from?

Answer 8

Basement membrane

Question 9

Describe the prickle cell layer

Answer 9

Larger polyhedral cells,
Lots of desmosomes (connections)
Intermediate filaments connect to desmosomes

Question 10

How many flatter layers does the Granular layer have?

Answer 10

2-3

Question 11

What do Large keratohyalin granules contain?

Answer 11

structural filaggrin & involucrin proteins

Question 12

Describe the granular layer

Answer 12

Odland bodies
High lipid content
Cornified envelope origin
loses the cell nuclei

Question 13

What do lamellar granules do?

Answer 13

release lipids

Question 14

What are corneocytes?

Answer 14

Overlapping non-nucleated cell remnants

Question 15

What do melanosomes do?

Answer 15

Convert tyrosine to melanin pigment

Question 16

Describe Langerhans cells

Answer 16

mesenchymal origin (bone marrow)
Prickle cell layer
also found in lymph nodes and dermis
linked with imune system
antigen presenting cells

Question 17

Describe Merkel cells

Answer 17

basal
between keratinocytes and nerve fibres
mechanoreceptors

Question 18

What are the 3 phases of hair growth?

Answer 18

Anagen - growing
catagen - involuting
Telogen = resting