Dermatitis / eczema Flashcards
What is hyperkaratosis?
increased thickening of keratin layer
What is parakeratosis
persistence of nuclie in the keratin layer
What is Acanthosis
increased thickenss of epidermis
What is papillomatosis?
irregular epithelial thickening
What is spongiosis?
Oedema between keratinocytes
What is inflammatory cell infiltrate?
Acute or chronic lymphocytes and/or neutrophils
What happens in acute itch?
papulovascular, red lesions (erthematous), oedema (spongiosis), ooze or scalling & crusting
What happens in chronic itch?
thickening (lichenification), elevated plaques,
increased scaling
What are chronic changes within atopic eczema?
Lichenification
Excoriation
Secondary infection
What virus portays monomorphic punched out lesions?
Herpes Simplex Virus
What gene is most importnt in eczema?
Filaggrin
What’s a sign of Chronic Acitinic Dermatitis?
cute off points e.g. at collar
