Pruritis Flashcards
1
Q
Name some chemical mediators of the skin
A
histamins
PGE2
acetylcholine, serotonin, kallikrein, IL2, substance P tryptase
2
Q
Nerve transmission mediators
A
unmylinated C fibres,
3
Q
Name 4 casues of itch
A
Pruritoceptive
neuropathic
neurogenic
psychogenic
4
Q
Name systems that when diseased can cause itch
A
heamatological paraneoplastic liver and bile duct psychogenic kidney and thyroid disease
5
Q
Describe psychogenic itches
A
psychological causes with no (current) detectable CNS damage
6
Q
Describe Neurogenic itch
A
no evident CNS damage nut itch is caussed by e.g. opiate effects on CNS receptors