Pruritis Flashcards

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1
Q

Name some chemical mediators of the skin

A

histamins
PGE2
acetylcholine, serotonin, kallikrein, IL2, substance P tryptase

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2
Q

Nerve transmission mediators

A

unmylinated C fibres,

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3
Q

Name 4 casues of itch

A

Pruritoceptive
neuropathic
neurogenic
psychogenic

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4
Q

Name systems that when diseased can cause itch

A
heamatological
paraneoplastic
liver and bile duct
psychogenic
kidney and thyroid disease
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5
Q

Describe psychogenic itches

A

psychological causes with no (current) detectable CNS damage

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6
Q

Describe Neurogenic itch

A

no evident CNS damage nut itch is caussed by e.g. opiate effects on CNS receptors

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