Infections of the skin Flashcards

1
Q

What virus causes chickenpox and shingles

A

Varicella/Herpes Zoster Virus

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2
Q

What complications can arise of chickenpox?

A
secondary bacterial
Pneumonitis
haemorrhagic
scarring, absent or minor
Encephalitis
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3
Q

What can cause neonatal VZV?

A

Secondary to chickenpox in mother in late pregnancy.

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4
Q

What can prevent Neonatal VZV?

A

Varicella Zoster Immune Globulin

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5
Q

Describe shingles

A

Dermatomal distribution

Reactivation of varicella zoster virus

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6
Q

What is opthalmic zoster?

A

Where shingles affects the opthalmic division of the trigeminal nerve. Urgent referral is indicated.

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7
Q

If the shingles is covering the mouth/nose region it is covering what region of the trigeminal nerve?

A

Maxillary division of the trigeminal nerve

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8
Q

If the shingles is covering the ‘jaw line’ what division of the trigeminal nerve is it covering?

A

mandibular division

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9
Q

Explain Ramsay-Hunt syndrome

A

Vesicles and pain in auditory canal and throat.
- poorer prognosis than Bell’s palsy
irritation of the 8th cranial nerve

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10
Q

What can the patient suffer with RHS?

A

deafness
vertigo
tiinitus

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11
Q

What is another name for RHS?

A

Geniculate or otic herpes zoster

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12
Q

Is the chicken pox vaccine live attenuated? True or False

A

True

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13
Q

How effective is the vaccine for shingles in the elderly?

A

decrease in shingles by 38%

decrease in post herpetic neuralgia by 67%

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14
Q

What causes primary gingivostomatitis and what does the patient suffer?

A

Herpes Simplex Virus

extensive ulceration in and around the mouth for around a week

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15
Q

Describe what HSV type 1 can cause

A

oral lesions
genital herpes
ecephalitis

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16
Q

Describe what HSV type2 can cause

A

genital herpes,
encephalitis
disseminated infection (neonates especially)

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17
Q

What can be used to treat VZV and HSV?

A

Aciclovir and Guanosine

18
Q

What tests would you carry out?

A

Viral swab

Antibody tests

19
Q

What viruses can cause Erythema multiforme?

A

HSV and Mycoplasma pneumoniae bacterium

20
Q

What happens with erythema multiforme?

A

Target lesions with erythema, may have drug triggers

21
Q

Describe Molluscum contagiosum

A

fleshy, firm, umbilicated, pearlescent nodules (1-2mm in diamteter)
can be sexualy transmitted and take months to dissapear

22
Q

What can be used to treat Molluscum contagiosum?

A

Local application of liquid nitrogen

23
Q

What causes warts

A

Human papilloma virus type 1-4 (there are >80 types)

24
Q

What types of HPV cause genital warts?

25
What types of HPV cause cervical cancer?
16 and 18
26
What types does the vaccine protect against?
6, 11, 16 and 18
27
What causes Herpangina ?
Enterovirus | coxsackie virus and echovirus
28
What causes hand, foot and mouth disease?
Enteroviruses esp. coxsackie virus
29
What causes eryhtema infectiosum (slapped cheek disease)
Parvovirus
30
What complications are associated with parvovirus B19?
Spontaneous abortion, aplastic cries chronic anaemia (immunosuppressed)
31
What lab test for parvovirus?
Parvovirus B19 IgM test
32
What is orf?
virus of sheep (scabby mouth) | farmers
33
What is primary infection of Syphilis?
Chancre, Painless ulcers at site of entry
34
What is second phase infection of syphilis?
red rash over body, prominent on soles of feet and palms mucous membrane 'snail track' ulcers
35
What is tertiary syphilis?
CNS, cardiovascular, gummatous etc
36
What bacterium causes syphilis?
Treponema pallidum
37
what tests are for syphilis?
blood test | swab of chancre for PCR
38
How do you treat syphilis?
Penicillin injections
39
Describe Lyme disease?
Vector (ticks), caused by Borrelia burgdorferi. Early erythema migrans and late heart block, nerve palsies and arthritis.
40
How do you treat Lyme disease?
Doxycyline or amoxicillin
41
How do you test for Lyme disease?
Antigen test