Stroke:pathology and investigation Flashcards
What is a stroke?
Neurological deficit of sudden onset lasting more than 24 hrs of vascular origin
What is a Transient ischaemic attack?
less than 24hrs
neuro deficit
of vascular origin
What are the symptoms of stroke?
- Lose of power
- Loss of sensation
- Loss of speech
- Loss of vision
- Loss of coordination
What does photophobia suggest?
haemorrhage
What is dysarthria
the muscles you use for speech are weak or you have difficulty controlling them
What is dysphasia?
language disorder marked by deficiency in the generation of speech, and sometimes also in its comprehension, due to brain disease or damage
What is nystagmus?
“jiggly eyes” rapid jerking movements
What causes a stroke?
Blockage of a blood vessel by thrombus or embolus to brain
OR
due to haemorrhage
What links anterior and posterior circulation of the brain?
Circle of Willis
What does the carotid system supply?
Most of the hemispheres and cortical deep white matter
What does the vertebro-basilar system supply?
Brain stem
cerebellum and occipital lobes
What is frontal lobe responsible for?
Judgement
foresight
Voluntary movement
What is Broccas area responsible for?
Speech
What is the temporal lobe responsible for?
intellectual and emotional functions
What is the brainstem responsible for?
Swallowing
Breathing
heartbeat
wakefulness centre and other involuntary functions
What is the cerebellum responsible for?
Co-ordination
What is wernicke`s area responsible for?
Speech comprehension
What is the occipital lobe responsible for?
Primary visual area
What is the temporal lobe also responsible for?
Hearing
What is the parietal lobe for?
Comprehension of language
What is the sensory cortex responsible for?
Pain heat and other sensations
In deep white matter where will a stroke be most devasting and why?
The internal capsule
and Pons
Major effect as fibres are packed close together
What are the 4 causes of a stroke?
- Blockage of a vessel with clot or thrombus
- Disease of vessel wall
- Disturbance of normal properties of blood
- Rupture of vessel
What is the commonest cause of a cardioembolic stroke?
Atrial fibrilation
What is a small vessel of a stroke called?
Lacunar
What are the rarer causes of a stroke?
Carotid dissection (idiopathic or stroke)
What are the subtypes of stroke?
- TACS: Total anterior circulation stroke
- PACS: Partial anterior circulation stroke
- LACS: LAcunar stroke
- POCS:Posterior circulation stroke
What does left optic nerve compression result in?
Unilateral field loss
What does chiasmal compression from pituitary tumour/thrombus
Bitemporal hemianopia
What does left cerecrovascular event result in?
Homonymous hemianopia
What percentage of strokes TACS?
20%
What are the symptoms of a TACS?
Weakness sensory deficit Homonymous hemianopia (loss of vision) Higher cerebral dysfunction (dysphasia, dyspraxia)
What is TACS usually caused by?
Occulsion of proximal middle cerebral artery or ICA
What percentage of strokes are PACS?
35%
What are the symptoms of a PACS?
- One limb
- Face and hand
- higher cerebral dysfunction
(2/3 of the above)
What causes PACS?
Middle Cerebral Artery
What percentage of strokes are LACS?
20%
What are the four types of LACS?
- Pure motor
- Pure sensory
- Sensorimotor
- Ataxic hemiparesis
Describe a pure motor LAC?
Complete or incomplete weakness of 1 side, involving the whole of 2 of 3 body areas (face/arm/leg)
Describe a pure sensory LAC?
Sensory symptoms involving the whole of 2/3 body areas
Describe an ataxic hemiparesis LAC?
Hemiparesis and ipsilateral cerebellar ataxia
Small infarcts in basal ganglia or pons.
Intrinsic disease of single basal perforating artery (end arteries).
What is ataxia?
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.
What percentage of strokes are POC`s?
25%
What is affected during POCs?
Brainstem,cerebellar or occipital lobes
What is the normal presentation of POCS?
There is none
ahahahaha
variable and complex
What are the modifiable risk factors for a stroke?
- High blood pressure
- Atrial fibrillation
What are the non-modifiable risk factors for stroke?
- Age
- Race
- Family history