Stroke and TIA Flashcards

1
Q

what is a stroke

A

rapid development of symptoms/signs
focal loss of cerebral function
global loss with coma or SAH
lasts > 24 hours
presumed vascular origin

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2
Q

what are the 2 types of stroke

A

ischaemic stroke
haemorrhage stroke

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3
Q

what is shown in the image

A

ischaemic stroke, left
haemorrhage stroke, right

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4
Q

how does an ischaemic stroke happen

A

artherosclerosis causes a thick, rough deposit to form on the inner wall of an artery blocking the passage way or narrowing it
only small amount of blood can get through
OR: a blood clot gets stuck in an artery and blocks the blood flow

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5
Q

how does a haemorrhage stroke happen?

A

blood from burst artery is forced into the tissue of the Brian (intracerebral haemorrhage) or into the narrow space between the brain surface and the layer of tissue that covers the brain (subarachnoid haemorrhage)

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6
Q

intra-cerebral haemorrhage

A

bleed form a blood vessel
variable prognosis
occasionally from an AVM or tumour

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7
Q

how does infarction occur

A

thrombosis in situ
thrombus forms at site of a hardened patch of artery within the brain
usually affects the small blood vessels in the brain

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8
Q

how does infarction occur

A

thrombosis in situ
thrombus forms at site of a hardened patch of artery within the brain
usually affects the small blood vessels in the brain

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9
Q

main risk factors for thrombosis in situ

A

hypertension
smoking
lipids

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10
Q

embolic stroke

A

thrombus forms outside the brain and embolisms to the brain

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11
Q

main risk factors for embolic stroke

A

atrial fibrillation
cardiac failure
valvular disease
diabetes
lipids

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12
Q

what is a TIA

A

transient ischaemic attack
acute loss of focal cerebral function
or
acute monocular visual loss (amaurosis fugax)
lasts <24 hours but mostly short lived

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13
Q

scheme for noticing signs of stroke

A

FAST
f- face
a- arms
s- speech
t- time

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14
Q

what is the scale used in stroke assessment

A

ROSIER
recognition of stroke in the emergency room

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15
Q

what is the ROSIER scale

A

in acute stroke rapid intervention is crucial to maximise early treatment benefits
validated scoring system to identify patients with acute stroke from myriad other non stroke condiotns would be helpful

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16
Q

what does the image show

A

ROSIER scale

17
Q

taking stroke history

A

time of onset of symptoms
parts of the body affected
nature of symptoms, positive or negative
accompanying symptoms
previous TIA.stroke
past medical history (vascular)
family history
lifestyle

18
Q

questions to ask if patient has suddenly..?

A
19
Q

risk factors for stroke and TIA

A

age
family history
smoking
alcohol
recreational drugs
hypertension
diabetes
raised cholesterol
ischaemic heart disease
peripheral vascular disease
atrial fibrillation

20
Q

classification of stroke

A

anterior (carotid) system
posterior (vertebrobasillar) system

21
Q

common stroke symptoms for the middle cerebral artery

A

parietal, frontal, superior temporal lobes
contralateral
UMN facial weakness
hemiplegia (arm > leg)
hemianopia
aphasia (dominant)
visuospatial problems (non- dominant)
PARTIAL SYNDROMES ARE COMMON

22
Q

common stroke syndrome for vertebral and basilar arteries

A

brain stem & cerebellum
diplopia, disorders of eye movements
nystagmus, vertigo, vomiting
dysarthria, dysphagia, bulbar weakness
ipsilateral LMN facial weakness
respiratory failure, coma
contralateral hemiparesis, quadriparesis

23
Q

what is the Bamford classification

A

The Bamford classification divides people with stroke into four different categories, according to the symptoms and signs with which they present. This classification is useful for understanding the likely underlying pathology, which in turn gives information on treatments likely to be useful and the prognosis. It is a relatively simple, robust, bedside classification using clinical information.

24
Q

rankin scale

A
25
Q

alteplase

A

known as r-tPA
no other thrombolytic is licensed for intravenous thrombolysis in acute stroke

26
Q

how is alteplase administered

A

each box contains 2 bottles
1 with the rug in powdered form
1 sterile water for injections
1 transfer canula to dissolve the drug
calculate the dosage from patients weight
draw up 10% of the normal dose into 10ml syringe and give as slow IV push over 1 minute
draw up 90% into 50ml infuse over 1 hour

27
Q

limitations of IV rtPA

A

generalisability
major strokes are difficult
increased risk of sICH with larger stroke

28
Q

what if IV thrombolysis is ineffective

A

consider intra-arterial therapies
age < 60
major stroke with proven proximal middle cerebral artery thrombus on Ct angiography
no sign of rapid improvement with IV thrombolysis
rapid transfer to RVI neurosciences
request Ct head and CTA in patients younger than 60 with signs of major stroke

29
Q

intra-arterial therapies

A

intra-arterial clot removal
intra-arterial thrombolysis

30
Q

recanalisation actuellement ischemic stroke
endovascular treatment

A

contraindication to IV rtPA
no change in NIHSS score one hour following administration of IV rtPA
3 hour treatment window has expired but less than 10 hours
severe neurological deficits in NIHSS > 16
treatment within 8 hours longer in some cases such as posterior circulation
IV/IA rtPA
merci retrieval device
penumbra aspiration device

31
Q

endovascular treatment

A

femoral or radial access
series of catheters: sheath, guide catheter, micro catheter
wire navigation