Acute neurological issues Flashcards

1
Q

meningitis type symptoms

A

headache
nucal rigidity
photophobia
fever
altered consciousness
neurological sings
purpuric rash

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2
Q

septicemia type symptoms

A

cold hands
fever
mottled skin
low BP
confused

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3
Q

emergency management of meningitis

A

emergency hospital transfer
stabilise ABC
monitor NEWS and GCS
readmission antibiotics
manage sepsis
antibiotic treatment, empirical then targeted

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4
Q

which comes first scan or LP

A

scan

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5
Q

when would a scan be performed

A

focal neurological signs
presence of papilloedema
uncontrolled seizures or septic shock
GCS 12 or less

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6
Q

risk factors for acute bacterial meningitis

A

infants
teens
young adults
elderly
pregnant
immunosuppressed
smoker
alcoholism
IV drug use
foreign travel
CSF shunt
splenectomy
crowding

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7
Q

status epilepticus

A

Convulsive status epilepticus is a life-threatening neurological condition defined as five or more minutes of continuous seizure activity or repetitive seizures without regaining consciousness between episodes.

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8
Q

classification of status epilepticus

A

convulsive and non-convulsive

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9
Q

convulsive

A

complete loss of awareness with stiff rigid limbs
and/or incontinence and tongue biting
period of recovery/confusion
often focal onset

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10
Q

non-convulsive

A

loss of consciousness or confusion
without any involuntary movements
seizure activity seen on EEG

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11
Q

causes of status epilepticus

A

epilepsy
metabolic problem
infection
recreational drug abuse/overdose
low blood sugar
underlying tumour
stroke
trauma

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12
Q

management of convulsive status epilepticus

A

emergency hospital admission
buccal midazolam in community
benzodiazepines e.g. lorazepam
stop seizure if prolonged
prevent further seizures
identify cause of seizure
protocol for treatment (phenytoin, levetiracetam)
potential ventilation and ICCU care

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13
Q

thunderclap headache

A

sudden onset of unusual severity reaching maximal intensity in under 1 minute

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14
Q

causes of sudden onset headaches

A

pituitary bleed
subarachnoid/ intercerebral haemorrhage
meningitis/ infections
cerebral bleed and/or tumour
arterial dissection
spontaneous CSf leak
cerebral venous sinus thrombosis
phaeochromocytoma
RCVS
idiopathic

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15
Q

primary vs secondary headaches

A

18% headaches are secondary

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16
Q

headache red flag features

A

sudden onset
severe to wake at night
associated vomiting
worse in morning/coughing/stooping
visual obscurations

17
Q

what is in the image

A

giant cell arteritis

18
Q

giant cell arteritis

A

systemic inflammatory granulomatous large essel vasculitis
disease of elderly
more women affected
unknown cause

19
Q

clinical presentation of giant cell arteritis

A

sudden
non specific: aching, malaise, weight loss, fever, loss appetite
headache in 2/3 temporal
proximal pain
jaw claudication
blurred vision then sudden visual loss
ache not weakness
co existent polymyalgia rheumatica

20
Q

examination findings in giant cell arteritis

A

swollen superficial temporal artery
check pulses
check options nerve and vision for anterior ischaemic optic neuropathy or retinal vessel occlusion

21
Q

investigations for giant cell arteritis

A

ESR usually over 50mm/h
CRP
temporal artery biospy
colour duplex ultrasonography

22
Q

risk of untreated giant cell arteritis

A

blindness
irreversible
stroke/ large vessel involvement
multi infarct dementia

23
Q

treatment of giant cell arteritis

A

treat with steroids at high dose
monitor ESR
titrate dose
watch for relapse

24
Q

management of giant cell arteritis

A

prevent further visual loss and systemic squealae of schema
steroids high dose
or low dose aspirin, methotrexate, toclizumab

25
acute spinal cord compression causes
trauma/fracture/dislocation tumour, metastatic: breast lung renal carcinoma, prostate thyroid and myeloma and lymphoma epidural abscess and infection disc/ spinal stenosis arthropathy
26
traumatic causes of acute spinal cord compression
via vertebral fracture or facet joint dislocation
27
infective causes of acute spinal cord compression
infections resulting in abscess formation can cause compression chronic infections typically seen with TB and fungal infections
28
disc prolapses causes of acute spinal cord compression
rare cause lumbar disc herniation typically causes compression of caudal equine inferior to spinal cord
29
most common cause of acute spinal cord compression
metastatic spinal cord compression
30
greater risk of spinal cord compression
any pathology that can predispose to narrowed cord canal so inflammatory conditions or degenerative conditions contributing to a spinal stenosis
31
red flags for spinal cord compression
elderly, major trauma steroids osteoporosis infection (fever, chills, weight loss, bacterial infection, immunosuppression, iv drug use) pain keeping up at night cancer history rheumatoid arthritits
32
examination of patient with spinal cord compression will guide to site of lesion
look for UMN pattern weakness reflexes increased sensory level planters upgoing clonus at ankle sphincter loss/ urinary retention nb spinal shock at onset if acute
33
management of acute spinal cord compression
urgent MRI contract neurosurgery or spinal team on call, high dose steroids/ transfer treatment depends on cause: surgery, antibiotics, steroids, radiotherapy risk of delayed treatment
34
MRI pre and post operative of spinal cord compression