Streptococcus pyrogenes

Question 1

Is Streptococcus pyrogenes gram positive or negative

Answer 1

positive

Question 2

Streptococcus pyrogenes shape?

Answer 2

chains

Question 3

What is Streptococcus pyrogenes inhibited by?

Answer 3

Bacitran

Question 4

Is Streptococcus pyrogenes a hemolytic or b hemolytic

Answer 4

B-hemolytic (streptolysin O > oxygen labile, antigenic; S > oxygen stable,, non-anitgenic)

Question 5

Is Streptococcus pyrogenes catalase postive or negative?

Answer 5

negative

Question 6

Is Streptococcus pyrogenes microaerophilic or obligate anaerobe?

Answer 6

microaerophilic

Question 7

What are the virulence factors Streptococcus pyrogenes?

Answer 7

1) M-protein (adherence factor, antiphagocytic, antigenic)
2) lipoteichoic acid (adherence factor)
3) steptokinase
4) hyaluronidase
5) DNAase
6) Anti-C5a peptidase

Question 8

Clinical Manifestations for Streptococcus pyrogenes

Answer 8

Direct Invasion/ toxin
a. pharyngitis (purulent exudates on tonsils fever, swollen lymph nodes)
b. sepsis 
c. skin infections 
d. scarlet fever 
e. toxic shock syndrome
Antibody-mediated 
a. rheumatic fever ( fever, myocarditis, arthritis, chorea, rash, subcutaneous nodules)
b. glomerulonephritis

Question 9

Treatment for Streptococcus pyrogenes

Answer 9

1) penicillin G
2) penicillin V
3) Erythromycin
4) Penicillinase-resistant penillicin (skin infections b/c might be staph