Staphylococcus aureus Flashcards
Where can Staphylococcus aureus be found?
- nose (upper resp tract)
- skin esp hospital staff and patients
- vagina
- lower urogenital tract
- gastrointestinal tract (GIT)
Is Staphylococcus aureus gram+ or gram-?
gram postive
Shape of Staphylococcus aureus?
grape like clustered cocci
Staphylococcus aureus culture?
a. B-hemolytic
b. golden w/ sheep blood
Is Staphylococcus aureus catalase pos or neg?
catalase postive
What are Staphylococcus aureus virulence factors (protective)?
a. microcapsule
b. protein A: binds IgG
c. Coagulase: fibrin formation around organism
d. hemolysis
e. leukocidins
f. penicillinase
What are Staphylococcus aureus virulence factors (tissue-destroying) ?
- hyaluronidase
- staphylokinase (lysis of clots)
- lipase
T/F. Staphylococcus are non-spore forming
T
What exotoxin-dependent clinical manifestations are caused by Staphylococcus aureus?
- gastroenteritis
- toxic shock syndrome ( fever, diarrhea, rash, hypotension, desquamation of palm and soles)
- scalded skin syndrome (children)
What are the direct invasion of organs with clinical manifestations for Staphylococcus?
- pneumonia
- meningitis
- osteomyelitis (children)
- acute bacterial endocarditis
- septic arthritis
- skin infection
- bacteremia/sepsis
- UTI
Is Staphylococcus aureus bacteriostatic or bactericidal
idk
What are the treatments for Staphylococcus aureus?
1) penicillinase-resistant penicillins
(eg. methicillin, nafcillin)
2) vancomycin
3) clindamycin
- if methicillin resistant, treat w/ IV vancomycin
T/F: Is Staphylococcus aureus an obligate aerobe or a facultative anaerobe?
Facultative anaerobe
Is Staphylococcus aureus coagulase-positive or negative?
positive
