STIs Flashcards
STIs that cause urethral or vaginal mucopurulent discharge:
Gonorrhea & Chlamydia
Agent that causes Gonorrhea
Neisseria gonorrhea; gram negative coccus
What is the most common cause of monoarticular joint inflammation in adults?
Gonorrhea
Dx for Gonorrhea / Tx for Gonorrhea
NAAT / Cephtriaxone (IM)
What STI do you treat along with Gonorrhea?
Chlamydia
Dx of Chlamydia / Tx of Chlamydia?
NAAT / Doxy 100 mg/day x 7 days or Azithromycin 1g x 1 time
What is the most reported STI in the US?
Chlamydia
What organism causes Chlamydia?
Chlamydia trachomatis (gram negative)
STIs that cause gential ulcers (5)
Syphilis, Cancroid, Granuloma Inguinale, Lymphogranuloma Venereum, Genital Herpes
Organism that causes Syphilis
Treponenema pallidum - spirochete
Primary Syphilis:
Painless chancre, lymphadenopathy, resolves in 4-6 weeks
Secondary Syphilis:
(weeks-months): non-puritic diffuse rash on body (doesn’t spare palms/soles), Condyloma Lata, mucous patch, flu symptoms
Tertiary Syphilis:
(15-20 years): CNS symptoms; gummatous syphilis, every organ infected.
Screening tests for Syphilis:
RPR / VRDL
Confirmatory tests for Syphilis:
FTA-ABS or MHA-TP
Tx for Syphilis stages 1 / 2 / 3
Pen G / Pen G / Pen G
Organism that causes Chancroid
Haemophilus ducreyi (gram negative rod)
Sx of Chancroid
PAINFUL vesicles, soft ulcer w/ necrotic base, weepy, one-sided lymphadenopathy
Dx / Tx of Chancroid
PCR / Azithromycin
Where is Chancroid found?
Developing Countries
Causative agent for Lymphogranuloma Venereum
Strain of Chlamydia
Population most often affected by Lymphogranuloma Venereum
MSM population in US (& developing countries)
Tx of Lymphogranuloma Venereum
Doxy x 21 days (long time)
Progression of Lymphogranuloma Venereum
1) Small ulcer @ inoculation site that heals in days, 2) swelling and inflammation of inguinal and femoral lymph nodes, 3) swelling, anal fistulas / scarring; “groove sign” - lymph nodes swelling around inguinal ligament
Dx of Lymphogranuloma Venereum
NAATs or PCR
What is the causative agent of Granuloma Inguinale?
Klebsiella granulomatis
Dx for Granuloma Inguinale / Tx for Granuloma Inguinale
Donovan bodies on a Wright Stain / Doxy
Uncommon “Tropical” disease
Granuloma Inguinale
Granuloma Inguinale is painless/painful?
painless
What is a difference between Granuloma Inguinale and Lymphogranuloma Venereum?
Granuloma Inguinale rarely spreads to the lymph nodes
Diseases that cause genital ulcers that are painful:
Chancroid, Herpes Simplex Virus
Diseases that cause genital ulcers that are painless:
Syphilis, Granuloma Inguinale
Presentation of Condyloma Acuminata:
Warts: cauliflower like, skin colored, hyperkeratotic warts
Which stage of Syphilis is contagious / NOT contagious?
Early / Late
Primary lesion of Syphilis:
painless chancre at lesion site and lymphadenopathy