STI Flashcards
Gonorrhoea
- Gonorrhoea is most commonly diagnosed in men who have sex with men, young (heterosexual) Aboriginal and Torres Strait Islander people
- travellers returning from high prevalence areas overseas.
- Neisseria gonorrhoeae, (Gram-negative)
Gonorrhoe - Clinical presentation
- often asymptomatic
- Penile urethral discharge
- Dysuria
- Vaginal discharge
- Dyspareunia with cervicitis
- Conjunctivitis: purulent, sight-threatening
- Anorectal symptoms: discharge, irritation, painful defecation, disturbed bowel function
Gonorrhoe - Complication
-
Epididymo-orchitis:
- Symptoms: Painful, red, swollen testicles.
- Frequency: Uncommon.
-
Prostatitis:
- Symptoms: Inflammation of the prostate.
- Frequency: Very rare.
-
Pelvic Inflammatory Disease (PID):
- Symptoms: Dyspareunia (painful intercourse), intermenstrual bleeding, post-coital bleeding, discharge.
-
Bartholin Gland Abscess:
- Symptoms: Swelling and pain in the Bartholin glands.
-
Disseminated Disease:
-
Symptoms:
- Skin: Macular rash, necrotic pustules.
- Joints: Septic arthritis.
- Other: Rarely, meningitis or endocarditis.
-
Symptoms:
Gonorrhea can lead to several complications, including epididymo-orchitis, prostatitis, PID, Bartholin gland abscess, and disseminated disease, which may present with skin rashes, septic arthritis, and, rarely, meningitis or endocarditis.
- Epididymo-orchitis (uncommon): painful, red swollen testicle/s
- Prostatitis (very rarely)
- Pelvic inflammatory disease (PID): dyspareunia, intermenstrual bleeding, post-coital bleeding, discharge
- Bartholin gland abscess
- Disseminated disease (rarely):
macular rash that may include necrotic pustules
septic arthritis - Meningitis or endocarditis (rarely)
Gonorrhoe - Diagnostic
- First pass urine (FPU) - NAAT
- Penile urethral swab ( just if discharge)
- Clinician-collected endocervical swab -best
- Clinician-collected endocervical swab (men)
- Pharyngeal swab (men)
Gonorrhoe - Treatment uncomplicated
- Ceftriaxone 500 mg IMI, stat. in 2 mL 1% lignocaine+ Azithromycin 1 g PO, stat.
same treatment in pregnancy
Gonorrhoe - Treatment Conjunctivitis
- Ceftriaxone 1 g IMI, stat. in 2 mL 1% lignocaine+
Azithromycin 1 g PO, stat.
Gonorrhoe - other MX
- no sexual contact for 7 days
- Partner notification and testing ( 2 month back)
- Notify health department
- Testing for other STIs
Chlamydia
- most commonly
- Those < 30 years are at greatest risk.
- Frequently asymptomatic.
- Simple to test and treat.
Chlamydia trachomatis
Chlamydia - Symptoms
85%-90% have no symptoms
- Dysuria
- Penile urethral discharge
- Vaginal discharge
- Testicular pain
- Pelvic Pain
- Intermenstrual bleeding
- Postcoital bleeding
- Pain with sex - dyspareunia
- Anorectal symptoms
Clamydia - complications
- Epididymo-orchitis
- Pelvic inflammatory disease (PID)
- Infertility
- Pregnancy - Ectopic pregnancy, Premature rupture of the membranes, preterm delivery, and low-birthweight infants
- Reactive arthritis: arthritis, sometimes with concurrent rash and gastrointestinal symptoms
- Cervicitis
- Conjunctivitis
- Perihepatitis
Clamydia - Diagnostic
- First pass urin ( NAAT)
- Endocervical swab
- Anorectal swab
- Pharyngeal swab
NAAT highly sensitive
Chlamydia - Treatment
For uncomlicated genital or pharyngial
* Doxycylin 100 mg for 7 days
* Alternative Azithromycin 1g, immed.
Anorectal asymptomatic
* Doxycylin 100 mg for 7 days
* Alternative Azithromycin 1g, immedi repeat in 12-24 hrs
Anorectal symptomatic
* Doxycylin 100 mg for 21 days
* Alternative Azithromycin 1g, stat repeat in 12-24 hrs
Chlamydia - further MX
- No sexual contact for 7 days or until symptoms resolved
- Contact tracing and testing 6 month
- notify health department
Pregnancy : Azythromycin 1g immed
Retest in 3 month
Syphillis
- high prevalence : homosexual, Abor/torres
- in pregnancy - congenital syphylis ( urgent specialist advice
Treponema Palidum
Syphillis- Clinic
- 50% asymptomatic
- mimic many other conditions , consider testing in all pat with unexplained symptoms
- 3 stages
early infectious
late latent
tertiary or late symptomatic