Steven-Johnson Syndrome Flashcards
1
Q
What is Steven-Johnson syndrome?
A
Acute skin hypersensitivity reaction
EMERGENCY
2
Q
What can trigger SJS?
A
Allopurinol Salicylates Anti-convulsants HSV Group B strep
3
Q
Where does SJS affect?
A
Mucosal sites (at least 2 affected)
4
Q
What are the features of SJS?
A
Prodrome
- fever
- non-specific URTI
Tender skin rash
- macules
- flaccid blisters
- on trunk
Severe ulceration of mucosa
Nikolsky +ve
5
Q
How is SJS investigated?
A
Bloods
Skin biopsy
6
Q
How is SJS diagnosed?
A
Skin detachment <10%
Widespread erythematous or purpuric macules
7
Q
How is SJS managed?
A
ICU
Remove cause
IV fluids + electrolytes
Analgesia
8
Q
What is TEN?
A
Toxic epidermal necrolysis
Worse SJS
9
Q
What is the criteria for TEN?
A
Skin detachment >30%
