Pemphigus Vulgaris Flashcards
1
Q
What is pemphigus vulgaris?
A
Autoimmune intra epidermal skin condition
2
Q
Where does pemphigus vulgaris commonly affect?
A
Mucous membranes
3
Q
What is the pathophysiology of pemphigus vulgaris?
A
Antibodies against desmosomes
4
Q
What are the features of pemphigus vulgaris?
A
Flat flaccid blisters
Easily erode
Commonly in the mouth
5
Q
How is pemphigus vulgaris differentiated from bullous pemphigoid?
A
Pemphigus vulgaris = Nikolsky +ve
Bullous pemphigoid = Nikolsky -ve
6
Q
How is pemphigus vulgaris diagnosed?
A
Refer to dermatology
Skin biopsy
7
Q
How is pemphigus vulgaris managed?
A
High does oral corticosteroids
