Acanthosis Nigricans Flashcards
1
Q
What is acanthosis nigricans?
A
Hyperpigmentation and hyperkeratosis of skin
2
Q
What is hyperpigmentation?
A
Darkening of skin
3
Q
What is hyperkeratosis?
A
Thickening of the skin
4
Q
Where does acanthosis nigricans tend to affect?
A
Skin folds
5
Q
What are the features of acanthosis nigricans?
A
Symmetrical
Dark plaques
6
Q
What other features as associated with acanthosis nigricans?
A
Psoriasis
Skin tags
Papillomatosis
7
Q
What are the types of acanthosis nigricans?
A
Benign
Malignant
8
Q
What is benign acanthosis nigricans?
A
Thick velvetly lesions
Common in darker skinned individuals
9
Q
What is malignant acanthosis nigricans?
A
Associated with internal malignancy
- commonly GI
10
Q
What are causes of acanthosis nigricans?
A
Insulin resistance PCOS Obesity DM Prader-willi syndrome Acromegaly Cushing's disease Hypothyroidism
11
Q
How is acanthosis nigricans managed?
A
Treat underlying cause
- weight loss
- DM management
