Steroid Hormones/Lipids Flashcards

1
Q

Vertebrates hormones are divided into?

A

Steroid hormones, peptide hormones and amino acid hormones

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2
Q

Steroid hormones can be grouped(sourced) into? a)….. b)…..c)…..d)….

A

Ovarian steroid hormones(C18), testicular hormones(C19), Adrenal Cortical Hormones (C21) and Corpus luteal hormones

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3
Q

B-estadiol,Estriol and estrone are steroids produced in the ?

A

Ovary I.e they are ovarian hormones/steroids

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4
Q

Testicular hormones steroids are from the ……….. And …………

A

Testes and adrenal gland(medulla part,)

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5
Q

The testiculaer hormones produced by the testes itself are

A

Testosterone, androsterone, dehydroepiandrosterone

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6
Q

Steroid hormones from the adrenal cortex include?

A

Mineralocorticoids ; Aldosterone, deoxycotecostero e and gluco corticoids; cortisone cortisol by corticosteroid

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7
Q

Progesterone is a steroid produced where?

A

In the corpus luteum

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8
Q

Steroid hormones are clasifiedinto

A

Glucocorticoids,mineral ocorticoids, androgens,estrogens and progesterone.

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9
Q

….is a synthetic product with estrogenic activity?

A

Stilbesterol

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10
Q

A derivative of stilbesterol which is physiologically more potent is …….

A

Dethystilbesterol

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11
Q

Androgens are chemically derived from….

A

a C19 Hydrocarbon; androstane

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12
Q

3 hormones with androgenic activities secreted by the testes

A

1) Testosterone(C19H28O2)
2) Androsterone(C19H30O2)
3) Dehydroepiandrosterone(C19H25O2)

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13
Q

The most potent of all androgenic hormones is ?

A

Testosterone

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14
Q

DHEA production peaks between age ….. and ……

A

25&30

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15
Q

The relative potency of the testicular(androgenic) hormones is (From testosterone to DHEA)

A

20:7:1

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16
Q

Few testicular hormones produced by the adrenal glands are

A

Androst-4-ene-3,17-dione.

Androst-4-ene-3, 11,17-trione

17
Q

Biosynthesis of testosterone

A

From Cholesterol>prenenolone>progesterone>hydroxyprogesterone>Testosterone

18
Q

List the steps in the Biosynthesis of testosterone

A

From Cholesterol>prenenolone>progesterone>hydroxyprogesterone>Androstenedione>Testosterone

19
Q

Androstenedione and DHEA are synthesized where?

A

In the testes

20
Q

DHEA is secreted more than testosterone in normal male.True or false?

A

True

21
Q

Metabolic transformation of androgens takes place in the

A

Liver

22
Q

During androgen metabolism in the liver. The two reactions that occur are

A

a)Testosterone to androst-4-ene-3, 17-dione

b( interconversion of 3-hydroxy and 3-Keto derivatives.

23
Q

List the functions of androgen s

A

a),b)

24
Q

High dose of testosterone leads to

A

Atrophy of sperm