Stem cells questions

Question 1

What are features of stem cells?
1. All stem cells are totipotent
2. Stem cells can selfrenew for long periods of time
3. Stem cells are always quiescent
4. Stem cells can generate differentiated cells
5. Adult stem cells all express the same markers irrespective of the tissue

Answer 1

Stem cells can self-renew for long periods of time.
Stem cells can generate differentiated cells

Question 2

Aged stem cells always become cancer cells

Answer 2

False

Question 3

Melanocyte stem cells expand upon aging.

Answer 3

False

Question 4

Aged hematopoietic stem cells show imbalanced differentiation towards myeloid lineage

Answer 4

True

Question 5

All aged stem cells have undergone the same number of cell divisions

Answer 5

False

Question 6

Quiescent hematopoietic stem cells primarily use non-homologous end joining to repair DNA

Answer 6

True

Question 7

Epigenetic changes contribute to stem cell aging

Answer 7

True