Lecture 11 Flashcards
1
Q
To which AA does ubiquitin bind?
A
It binds with its C-terminus to lysine
2
Q
What is the lysosomal pathway?
A
Phagophore formation
fusion with lysosome
autolysosome
3
Q
What are the two different lysosomal pathways called?
A
Makro autophagy (destroys everything)
slective autophagy (destroys selectively)
4
Q
What is proteostasis collapse?
A
Overproduction of proteins/missfolding etc due to stress
5
Q
What are microRNAs?
A
hairpin dsRNA regulate mRNA by antisense pairing
processed by DICER
infere with translation
