Lecture 18 Flashcards
1
Q
What is a holobiont?
A
An organism and its associated microbiome
2
Q
What are the roles of the gut microbiota?
A
immuno-modulation
protection against pathogens
nutrient aquisition
3
Q
How can drugs influence the gut microbiota?
A
- Transformation of drugs -> make them toxic
- Shut down metabolism
- Reduces drug effect
- Retargeting of initial drug target to new target