Statins Flashcards
1
Q
Indications
A
- Primary prevention of cardiovascular disease
- Secondary prevention of cardiovascular disease
- Primary hyperlipidaemia
2
Q
Mechanism of action
A
Inhibition of HMG CoA reductase - enzyme involved in making cholesterol
3
Q
Adverse effects
A
Headache
GI disturbances
4
Q
Warnings
A
Use caution in hepatic impairment
Reduce dose in renal impairment
5
Q
Interactions
A
Avoid concurrent use of macrolides or other P450 inhibitors
6
Q
Prescribing
A
PO
7
Q
Administration
A
Usually taken in evening
