Staphylococcal Scalded Skin Syndrome

Question 1

basic pathology of staphylococcal scalded skin syndrome

Answer 1

type of staphylococcus aureus produces epidermolytic toxins.
protease enzymes that break down the proteins that hold skin cells together.
leading to loss of the epidermis

most commonly occurs within 48 hours of birth and children <5

Question 2

presentation of staphylococcal scalded skin syndrome

Answer 2

initially non specific symptoms: irritability, fatigue, fever
within 48 hours: wide spread erythematous rash
bullae form and rupture easily

no mucosal involvement

Question 3

what sign is positive in staphylococcal scalded skin syndrome

Answer 3

Nikolsky sign - very gentle rubbing of the skin causes it to peel away.

Question 4

management of staphylococcal scalded skin syndrome

Answer 4

admission for IV ABX
management of fluid and electrolyte disturbance
majority make recovery without scarring

Question 5

complications of staphylococcal scalded skin syndrome

Answer 5

if untreated can lead to secondary infection and sepsis
scarring
hypothermia
dehydration
renal failure