Motor Neurone Disease Flashcards
1
Q
what is MND
A
progressive degeneration of UMN and LMN
2
Q
risks for MND
A
Age
M>F
genetic predisposition
some links to smoking and pesticide
3
Q
presentation of MND
A
weakness - often noticed in upper limbs first
fatigue on exertion
face, speech and swallowing affected
breathing difficulties
4
Q
LMN signs
A
muscle wasting
reduced tone
fasciculations
hypo-reflexia
5
Q
UMN signs
A
hypertonia
spasticity
brisk reflexes
Babinski signs
6
Q
which medication can be used in MND
A
riluzole
prevents stimulation of glutamate receptors (generally used in ALS )
7
Q
apart from medication what can increase survival in MND
A
NIV at night
PEG tube/ nutritional support
