Motor Neurone Disease Flashcards

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1
Q

what is MND

A

progressive degeneration of UMN and LMN

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2
Q

risks for MND

A

Age
M>F
genetic predisposition

some links to smoking and pesticide

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3
Q

presentation of MND

A

weakness - often noticed in upper limbs first
fatigue on exertion
face, speech and swallowing affected
breathing difficulties

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4
Q

LMN signs

A

muscle wasting
reduced tone
fasciculations
hypo-reflexia

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5
Q

UMN signs

A

hypertonia
spasticity
brisk reflexes
Babinski signs

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6
Q

which medication can be used in MND

A

riluzole

prevents stimulation of glutamate receptors (generally used in ALS )

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7
Q

apart from medication what can increase survival in MND

A

NIV at night
PEG tube/ nutritional support

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