Gullian Barre Syndrome Flashcards
what is Guillain Barre Syndrome
acute paralytic polyneuropathy which affect the peripheral nervous system
what infections are linked with GBS
campylobacter jejuni
cytomegalovirus
Epstein-Barr virus
how can GBS present
acute, symmetrical, ascending weakness and can also cause sensory symptoms
reduced reflexes
why does GBS occur
molecular mimicry
antibodies produced for pathogen attack nerve cells
what is the clinical course of GBS
symptoms generally start within 4 weeks of infection
reach their peak within 2-4 weeks
and resolve slowly over months to years
what would lumbar puncture show on a patient with GBS
raised protein
which criteria is used for GBS
Brighton criteria
management for GBS
IV immunoglobulins
plasmapheresis
VTE prophylaxis
what is the risk with GBS
respiratory failure
will require intubation and ITU admission
