Staph.

Question 1

Mention the diseases caused by S. aurus.

Answer 1

1_focal suppuration
A_superfacial infections«carbuncles, boils, absesess
B_deep seated infections«osteomyelitis, bronchopneuomonia, Empyema, endocarditis, meningitis»

2_spread via lymphatics and blood«Bacterimia, septicaemia»
3_toxogenic disease «food poising, TSS, scaled skin syndrome.

Question 2

What’s the virulunce factors of s. arus

Answer 2

1_protective pn. 
P A binds IGg prevent opsonization, phagositosis» 
Coagulase
hemolysin
leukocidin
penicillinase
2_tissue destroying pn. 
Hyaluronidase
staphylokinase 
lipase
3_toxins
exofoliative toxin
enterotoxin
TSST.

Question 3

How can you treat S. aerus infection?

Answer 3

pencillinase resistant pencillin 
eg: dicloxacillin
oxacillin. 
Nafcillin
methicillin

in MRSA
vancomycin
clindamycin

Question 4

what’s the habitat for S. epidermis?

Answer 4

normal flira on skin, mucous mem.

Question 5

What’s the virulunce factors of S. epidermis?

Answer 5

glycocalyx adhere to forign bodies.
low-virulunce organism
no toxin

Question 6

what’s the disease caused by S. epidermis?

Answer 6

hospital accqierd disaese:
endocarditis on prosethtic heart valves, prosthetic hip infection, intravascular catheter inf., SCF shunt inf., neonatal sepsis.

Question 7

How do S. epidermis transmit?

Answer 7

usually it’s the own person bacteria which cause disease.

can be transmitted by hands

Question 8

what’s the lab diagnosis for S. epidermis?

Answer 8

gram stained mear
culture on blood agar: whitish, non. hymolytic colonies.
serological test is not useful

Question 9

how to differentiate between S. epidermis and S. saprophyticus?

Answer 9

S. epidermis is sensitive to novobiocin.

Question 10

how can you traet S. epidermis?

Answer 10

vancomycin +rifampicin or aminoglycosides.

have B. lactemase.

Question 11

what’s the disease caused by S. saprophyticus?

Answer 11

normal flora in vagina
cause community aquired urinary tract infection
in young sexually active women«GUT».