H. ifluenzi

Question 1

Is it capsulated or not?

Answer 1

some strains capulated typable b

some no, nontypable… all are pathogenic

Question 2

mention some other srains of heomophilus and their diseases

Answer 2

H. ducreyi.. chancroid STD
H. aegyptius… conjunctivitis, brazilian purpuric fever
H. parainfluenzae… pneumonia, endocarditid

Question 3

is it aerobic?

Answer 3

facultative

Question 4

how can we detect the capsule?

Answer 4

by idndian ink, or swelling with antisera

Question 5

culture media?

Answer 5

choclate agar, growth factor 5-10,co2 5_10%,

does not grow in normal blood agar

Question 6

what’s the viuralant factor?

Answer 6

invasive
capsule
IGA protease
LPS

Question 7

mention the diseases caused by H. influenzae?

Answer 7

type b:
main cause of meningitis in children
epiglottitis, septic arthritis, cellulitis, conjunctivitis.

non typable:
2 common cause of otitis media in children.
in adult: pneumonia, acute or chronic sinusitis in all ages

Question 8

how can we diagnose it?

Answer 8

blood culture except in conjunctivitis
CSF
synovial fluid
sputum in lower RT diseases

Question 9

what’s the treatment for H. inf

resistance?

Answer 9

cephalosporin for meningitis and epiglottitis
other inf,, ampicillin, bacterium, tetracycline, cefaclor.

resistance to:
Ampicillin
chloramphenicol