SSRI Flashcards
1
Q
SSRI drugs
A
Flouxetine
Paroxetine
Sertaline
Citalopram
“Flashbacks paralyze senior citizens”
2
Q
SSRI MOA
A
serotonine reuptake inhibitor
Normally takes 4-8 wks for antidepressant to take effect
3
Q
Clinical use
A
Depression, GAD, Panic disorder, OCD, Bulimina, Social phobias, PTSD
4
Q
Toxicity
A
Fewer than TCA:
GI distress
Sexual dysfunction (anorgasmia, low libido)
Serotonin syndrome
5
Q
Serotonin syndrome
A
Can be caused by anything that increases serotonin
(MAO, SNRI, TCAs)
Hyperthermia, Confusion, Myoclonus, CV collapse Flushing, Diarrhea, Seizure
Tx: cyproheptadine (5HT2 receptor antagonist)