Atypical antipsychotics Flashcards
1
Q
Atypical antipsychotics
A
Olanzapine Clozapine Quetiapine Risperidone Aripiprazole Ziprasidone
“It is atypical for OLd CLOSets to QUIETly RISPER from A to Z”
2
Q
MOA
A
Not understood
Varied effect on 5HT2, dopamine, and alpha and H1 receptor
3
Q
Clinical use
A
Schizophrenia: both positive AND NEGATIVE symptoms (vs. antipsychotics)
Bipolar, OCD Anxiety disorder Depression, Mania, Tourette's (associated with OCD)
4
Q
Toxicity
A
Fewer EPS and anticholinergic than traditional antipsychotic.
5
Q
Olanzapine and clozapine
A
Weight gain
“Oil and Carb make you FAT”
6
Q
Clozapine
A
agranulocytosis (weely WBC)
Seizure
7
Q
Ziprasidone
A
PRolong GT
ziPRasidone