SNRI Flashcards
1
Q
SNRI
A
Venlafaxine
Duloxetine
2
Q
MOA
A
Inhibit serotonin and NE reuptake
3
Q
Clinical use
A
Depression
Venlafaxine: also GAD and panic
Duloxetine: also diabeteic peripheral neuropathy
Duloxetine has greater effect on NE
4
Q
Toxicity
A
Increased BP most
Also stimulant effect, sedation, nausea