Major depressive disorder

Question 1

Duration

Answer 1

Lasting at least 6-12 months

Question 2

Diagnosis

Answer 2

5 symptoms for 6-12 months, or

9 symptoms for 2 or more weeks

Question 3

Symptoms

Answer 3

Sleep disturbance
Interest loss
Guilty or feeling of worthlessness

Energy reduction

Concentration loss
Appetite/weight change
Psychomotor retardation or agitation
Suicidality

Depressed mood

SIG E CAPS:

Question 4

Dysthymia

Answer 4

Milder form of depression lasting at least 2 years

also 2 years in cyclothymia composed of dysthymia and hypomanic

Question 5

Seasonal affective disorder

Answer 5

Symptoms associated with winter season;

Improves in response to full-spectrum bright light exposure

Question 6

Atypical depression

Answer 6

Differs from classic form of depression:

1) mood reactivity (being able to experience improved mood in response to positive events)
2) “reversed” vegetative symptoms (hypersomnia and weight gain)
3) leaden paralysis (heavy feeling and arms/legs)
4) long standing interpersonal rejection sensitivity

Most common subtype of depression

Tx: MAO inhibitor, SSRI.