SS3. Counter-current multiplication in kidney Flashcards
What are all the parts of the kidney from start to end?
Bowman’s capsule hugs glomerulus of nephron, collects fluid.
Proximal convoluted tube
Descends into loop of henle via descending and ascending limb.
Distal convoluted tubule
Juxtaglomerular apparatus
Collecting tubule/duct
Efferent branches off into smaller peritubular capillaries to reabsorb nurtiens. Meet in renal vein, where it’s passed through the rest of the body
What does Bowman’s capsule do?
Collects fluid from glomerulus
What does the proximal convoluted tube do?
Reabsorbs AA, Na+, Glucose H2O into blood –> 65% of all nutrients. Goes into Loop of Henle
Where can the Loop of Henle be found?
In the medulla
What does the descending limb of the Loop of Henle do?
Reabsorbs H2O, passively.
What does the ascending limb of the Loop of Henle do?
Reabsorbs Na2+, Cl, K.
Explain how the Loop of Henle is countercurrent multiplication?
H2O is reabsorbed passively due to active transport in the ascending limb which multiplies the H2O absorption
Where does the Loop of Henle meet lead to?
To the distal convoluted tubule.
What does the distal convoluted tubule do?
Responsible for reabsorption of other nutrients, like Na, Cl. Meets the glomerulus in a type of kiss via the juxtaglomerular apparatus that controls blood pressure.
Where do the distal convoluted tubules lead to?
To the collecting tubule/duct.
What is the function of the Collecing tubule/duct?
It reabsorbs H2O and Urea to increase the osmolarity in the medulla, and drive reabsorption of H2O in Loop of Henle.
What happens when everything has been reabsorbed?
Efferent arteriole branches off into peritubular capillaries that dance across the nephron where nutrients are reabsorbed. They meet again in the renal vein where it’s passed through the rest of the body.
