Spondyloarthropathies Flashcards

1
Q

What are spondyloarthropathies?

A

Group of conditions that effect the spine and peripheral joints

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2
Q

What conditions are spondyloarthropathies?

A

Ankylosing spondylitis
Enteropathic arthritis
Psoriatic arthritis
Reactive arthritis

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3
Q

What 7 features make spondyloarthropathies?

A
Sero negative
HLA B27 associated
Axial arthritis
Asymmetrical large-joint oligoarthritis 
Enthesitis - inflammation of insertio site of tendon/ligament
Dactylitis - inflammation of a digit
Extra-articular manifestations
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4
Q

What is ankylosing spondylitis?

A

Chronic inflammation of spine and sacro-illiac joints

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5
Q

What gene is associated with spondyloarthropathies?

A

HLA B27

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6
Q

What is the presentation of AS?

A

Low back pain
- worse at night
Morning stiffness

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7
Q

What are the extra-articular features of AS?

A
Anterior uveitis 
Aortic incompetence
AV block 
Apical lung fibrosis
Amyloidosis
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8
Q

What are the x-ray features of AS?

A

Dagger sign - central radio dense line

Sacroilitis

Bamboo spine - vertebral body fusion

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9
Q

How is AS managed?

A

Regular exercise
NSAIDs

TNF-a inhibitors

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10
Q

What is psoriatic arthritis?

A

Form of arthritis that effects those with psoriasis

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11
Q

What are the features of psoriatic arthritis?

A

Oligo-arthritis with dactylitis
Psoriatic plaques
Nail changes

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12
Q

What is the management for psoriatic arthritis?

A

NSAIDs
DMARDs
TNF inhibitors

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13
Q

What is reactive arthritis?

A

Sterile synovitis following an infection

  • dysentery (salmonella, shigella, campylobacter)
  • urethritis (chlamydia)
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14
Q

What is the presentation of reactive arthritis?

A

Days - 2 weeks adter infection
Asymmetrical lower limb arthritis

Skin changes

  • circinate balanitis
  • keratoderma blennorhagica

Conjuctivitis

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15
Q

What is circinate balanitis?

A

Ring shaped dermatitis on penis

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16
Q

What is keratoderma blennorhagica?

A

Waxy skin lesions found on palms and soles

17
Q

What is the management of reactive arthritis?

A

Treat infection

NSAIDs
Local steroid injections

18
Q

What is enteropathic arthritis?

A

Inflammation of joints associated with IBD

19
Q

What is type 1 enteropathic arthritis?

A

Oligoarthritis
Asymmetric
Correlation with IBD flares

20
Q

What is type 2 enteropathic arthritis?

A

Polyarthritis
Symmetrical
Less correlation with IBD flares

21
Q

How is enteropathic arthritis managed?

A

DMARDs

TNF inhibitors