Spondyloarthropathies Flashcards
What are spondyloarthropathies?
Group of conditions that effect the spine and peripheral joints
What conditions are spondyloarthropathies?
Ankylosing spondylitis
Enteropathic arthritis
Psoriatic arthritis
Reactive arthritis
What 7 features make spondyloarthropathies?
Sero negative HLA B27 associated Axial arthritis Asymmetrical large-joint oligoarthritis Enthesitis - inflammation of insertio site of tendon/ligament Dactylitis - inflammation of a digit Extra-articular manifestations
What is ankylosing spondylitis?
Chronic inflammation of spine and sacro-illiac joints
What gene is associated with spondyloarthropathies?
HLA B27
What is the presentation of AS?
Low back pain
- worse at night
Morning stiffness
What are the extra-articular features of AS?
Anterior uveitis Aortic incompetence AV block Apical lung fibrosis Amyloidosis
What are the x-ray features of AS?
Dagger sign - central radio dense line
Sacroilitis
Bamboo spine - vertebral body fusion
How is AS managed?
Regular exercise
NSAIDs
TNF-a inhibitors
What is psoriatic arthritis?
Form of arthritis that effects those with psoriasis
What are the features of psoriatic arthritis?
Oligo-arthritis with dactylitis
Psoriatic plaques
Nail changes
What is the management for psoriatic arthritis?
NSAIDs
DMARDs
TNF inhibitors
What is reactive arthritis?
Sterile synovitis following an infection
- dysentery (salmonella, shigella, campylobacter)
- urethritis (chlamydia)
What is the presentation of reactive arthritis?
Days - 2 weeks adter infection
Asymmetrical lower limb arthritis
Skin changes
- circinate balanitis
- keratoderma blennorhagica
Conjuctivitis
What is circinate balanitis?
Ring shaped dermatitis on penis