Sjogren's Disease Flashcards
1
Q
What is Sjogren’s?
A
Chronic autoimmune inflammatory disorder affecting secretions
2
Q
What is primary Sjogren’s?
A
Not associated with other diseases
3
Q
What is secondary Sjogren’s?
A
Associated with another underlying rheumatic disorder
4
Q
What is the pathophysiology?
A
Lymphocytic infiltration and fibrosis of exocrine glands - particularly lacrimal and salivary
5
Q
What are the symptoms?
A
Dry eyes Dry mouth Fatigue Raynaud's phenomenon Myalgia Arthralgia
6
Q
What is xerophthalmia?
A
Dry eyes
7
Q
What is xerostomia?
A
Dry mouth
8
Q
What investigations are done?
A
Anti-Ro antibodies
Anti-La antibodies
Schirmer’s test
Salivary gland biopsy
9
Q
What is Schirmer’s test?
A
Strip of filter paper under lower eyelid. Leave for 5 minutes.
<5mm is abnormal
10
Q
How is Sjogren’s managed?
A
Artificial tears
Suck sweets for saliva
Avoid dry atmospheres
11
Q
What are sicca symptoms?
A
Dry eyes
Dry mouth
