Giant Cell Arteritis Flashcards

1
Q

What is giant cell arteritis?

A

Chronic vasculitis of large and medium vessels

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2
Q

What is the age of onset?

A

> 55

median = 72

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3
Q

What is the gene associated with GCA?

A

HLA DR4

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4
Q

What are the symptoms?

A

New onset headache
Temporal artery tenderness
Jaw claudication

Visual symptoms

  • amaurosis fugax
  • blindess
  • diplopia
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5
Q

What is amaurosis fugax?

A

Painless temporary loss of vision in one or both eyes

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6
Q

What investigations should be done in suspected GCA?

A

ESR - raised

LFTs

Temporal artery biopsy

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7
Q

How is diagnosis made?

A

2 or more in patient >50

  • raised ESR, CRP or PV
  • new onset headache
  • tenderness or decreased pulsation of temporal artery
  • new visual symptoms
  • biopsy showing necrotizing arteritis
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8
Q

What is the management for GCA?

A

Prednisolone

Aspirin

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