Spondyloarthropathies Flashcards

1
Q

Name 4 conditions under the umbrella term of spondyloarthropathies

A

Ankylosing spondylitis
Psoriatic arthritis
Reactive arthritis
IBD associated arthritis

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1
Q

What gene is associated with spondyloarthropathies?

A

HLA B27

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2
Q

Do spondyloarthropathies generally present symmetrically or asymmetrically?

A

Asymmetrically

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3
Q

Are spondyloarthropathies typically seropositive or seronegative for RF?

A

Seronegative (unlike RA)

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4
Q

HLA-B27 is a specific subtype of MHC-I and associated to spondyloarthropathies. What does MHC-I do?

A

Major Histocompatibility Complex Class I molecules present antigens to cytotoxic T cells

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5
Q

What mnemonic is used for the general features of spondyloarthropathies

A

SPINEACHE

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6
Q

What does SPINEACHE stand for?

A

Sausage fingers (dactylitis)
Psoriasis
Inflammatory back pain
NSAIDs good response
Enthesitis (plantar fasciitis, inflamed heel tendon)
Arthritis
Crohn’s disease or Colitis
HLA B27
Eyes (uveitis)

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