Scleroderma Flashcards
Scleroderma is a _____ condition of which the most common type is l______ c______ scleroderma
systemic
limited cutaneous
What mnemonic helps to remember the symptoms of scleroderma?
CREST
What does C in CREST stand for (scleroderma)?
Calcinosis
Ca deposits in subcutaneous tissue, causes renal failure
What does R in CREST stand for (scleroderma)?
Raynaud’s
Digit ischemia due to sudden vasospasm
Often precipitated by cold and relieved with heat
What does E in CREST stand for (scleroderma)?
Esophageal dysmotility/strictures
Causes GI symptoms
What does S in CREST stand for (scleroderma)?
Sclerodactyly
Local skin thickening or tightening on fingers/toes
Causes movement restriction
What does T in CREST stand for (scleroderma)?
Telangiectasia
Spider veins
Risk of pulmonary hypertension
How is scleroderma diagnosed?
Anti Centromere Antibodies (ACAs)
Often ANA positive
How is scleroderma treated?
No cure
Treat symptoms
eg handwarmers for Raynaud’s
PPI for GI symptoms