Scleroderma Flashcards

1
Q

Scleroderma is a _____ condition of which the most common type is l______ c______ scleroderma

A

systemic
limited cutaneous

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2
Q

What mnemonic helps to remember the symptoms of scleroderma?

A

CREST

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3
Q

What does C in CREST stand for (scleroderma)?

A

Calcinosis

Ca deposits in subcutaneous tissue, causes renal failure

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4
Q

What does R in CREST stand for (scleroderma)?

A

Raynaud’s

Digit ischemia due to sudden vasospasm
Often precipitated by cold and relieved with heat

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5
Q

What does E in CREST stand for (scleroderma)?

A

Esophageal dysmotility/strictures

Causes GI symptoms

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6
Q

What does S in CREST stand for (scleroderma)?

A

Sclerodactyly

Local skin thickening or tightening on fingers/toes
Causes movement restriction

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7
Q

What does T in CREST stand for (scleroderma)?

A

Telangiectasia

Spider veins
Risk of pulmonary hypertension

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8
Q

How is scleroderma diagnosed?

A

Anti Centromere Antibodies (ACAs)
Often ANA positive

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9
Q

How is scleroderma treated?

A

No cure
Treat symptoms
eg handwarmers for Raynaud’s
PPI for GI symptoms

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