Reactive arthritis Flashcards
Reactive arthritis is s____ inflammation of synovial membranes and tendons, reacting to distant _____
sterile
infection
Name some causes of gastroenteritis
Campylobacter jejuni
Salmonella
Shigella
What 2 STIs can cause reactive arthritis?
Chlamydia trachomatis (most common)
Neisseria gonorrhoeae
What is the triad of symptoms seen in reactive arthritis called?
Reiter’s triad
What is Reiter’s triad?
Can’t see, can’t pee, can’t climb a tree
Uveitis
Urethritis
Arthritis
What is keratoderma blenorrhagicum
Brown discolouration, rash on sole of foot. Seen in reactive arthritis.
How do you differentiate between reactive arthritis and septic arthritis?
Septic arthritis is painful, hot, red and swollen joint. Also has signs or history of infection.
Joint aspiration
How do you diagnose reactive arthritis?
Joint aspirate first.
MC+S shows no organism
Plane polarised light microscopy is negative for crystalarthropathy
ESR and CRP is raised
HLAB27 positive
Sexual health review
Stool culture
How do you treat reactive arthritis?
NSAIDs
Steroid injection
Methotrexate
2nd line = anti-TNF-a inhibitor, infliximab
True or false: typically, reactive arthritis presents as an acute polyarthritis
False
Typically is acute monoarthritis, most commonly affecting the knee
How long do most cases resolve within?
6 months
Most do not recur
Recurrent cases may require…
DMARDs (eg methotrextate) or anti-TNF medications (eg infliximab)
What type of medication in methotrexate?
DMARD
What type of medication is infliximab?
anti-TNF