spleen Flashcards
spleen is surrounded by?
a connective tissue capsule
the parenchyma of the spleen is divided in to two
- red pulp
- white pulp
what does the white pulp & red pulp correspond to?
lymphocyte rich area (white)
blood rich area (red)
what forms the framework of the spleen
reticular connective tissue
what does the white pulp consist of?
-lymphocytic aggregations around the central arterioles
the central arteriole are branches of?
trabecular arteries which is a branch of the splenic artery
the white pulp is divided into 3 areas
-periarteriole lymphatic sheath (PALS)
-splenic nodule (malpighien nodules)
marginal zone
what is PALS and what does it consist of
- aggregation of l.c that surrounds the central arteriole,
- T-dependant area
- show thinkenings knows as splenic nodules
what is the splenic nodule
B-dependent area,the central arteriol surrounded by the splenic nodule has an eccentric position
what is the marginal zone? and what does it consist of?
- composed of loose lymphoid tissue
- region between red and white pulps
- contains marginal sinuses
- rich in macrophages
- B-depedant area
what does the red pulp consist of?
- splenic cords (cords of billroth)
- splenic sinuses
the splenic cords
- macrophages
- plasma cells
- cellular elements of blood
- ** all situated in the loose mesh work of the reticular cells
the splenic sinuses
are wide cavities, which are lined by discontinous endothelium there are wide spaces between these cells
what is around the splenic sinuses
the basal lamina which is discontinous,
riticular fibers surround sinuses mainly in a transverse direction
what are the endothelial cells of the sinuses called?
stave cells