Special Topics In Physiology Flashcards
What is the role of fat & skin in terms of regulation of body temperature?
Fat: insulator
Skin: radiator system (when cold: blood vessels constrict; when hot: dilate)
Most of the body heat is lost through which way?
Radiation > Evaporation > conduction to air > conduction to objects
What is the pathophysiology of fever?
Pyrogens -> increases IL-1 (alpha & beta), IL6 -> increases prostaglandins -> increases set-point temperature in hypothalamus
Excessive sweating causing fainting
Heat Exhaustion
High temperature causing tissue damage & impaired responses
Heat stroke
High temp secondary to the use of succinylcholine & halothane?
Malignant Hyperthermia
DOC for Malignant Hyperthermia
Dantrolene
Vasodilator
Keeps ductus arteriosclerosis
Prostaglandin E1
Antipyretic
Change in receptor in hypothalamus
Prostaglandin E2
Cell ATP, cell phosphocreatine
First 8-10 seconds
Ex: 100m dash, jumping, diving
Phosphagen energy system
Anaerobic; reconstitute ATP & phosphocreatine
For 1.3 top 1.6 minutes after Phosphagen system used up
Ex: tennis, soccer
Glycogen - Lactic Acid System
Aerobic; reconstitute ATP, phosphocreatine, glycogen-lactic acid cycle
? Carbohydrate loading
For unlimited time as long as with energy supply
Ex: long distance jogging
Aerobic system
What is the basis for muscle endurance?
Glycogen levels in diet
What is the best diet for muscle glycogen recovery?
High Carbohydrate diet
How long does it take to recover muscle glycogen?
2 days (high carb diet)