Sosnowski- Lung Cancer

Question 1

most lung cancer is what

Answer 1

metastatic cancer

Question 1

____ is the number one cancer-related cause of deaths in industrialized countries

Answer 1

primary lung cancer

Question 2

Answer 2

metastatic lung cancer

Question 3

1 cancer in males

Answer 3

prostate

Question 4

1 cancer in females

Answer 4

breast

Question 5

SCC, adenocarcinoma, and carcinoid tumor are what lung cancer

Answer 5

non small cell lung cancer (NSCLC)

Question 6

treated best with surgery

Answer 6

NSCLC

Question 7

derived from neuroendocrine cells

Answer 7

SCLC

Question 8

not curable by surgery due to probable metastasis at time of diagnosis

Answer 8

SCLC

Question 9

best treated with chemo and radiation

Answer 9

SCLC

Question 10

is NSCLC or SCLC more common

Answer 10

NSCLC

Question 11

_____% of lung cancer occurs in active smokers and those who have stopped recently

Answer 11

90%

Question 12

___ and ___ have strongest association w/ tobacco exposure

Answer 12

SCC and SCLC

Question 13

Answer 13

SCC

Question 14

pathophys includes squamous metaplasia

Answer 14

SCC

Question 15

centrally located

Answer 15

SCC

Question 16

Answer 16

SCC

Question 17

stained with cytokeratin

Answer 17

SCC

Question 18

peripherally located
most common in woman and nonsmokers

Answer 18

adenocarcinoma

Question 19

EGFR, KRAS, and ALK activating mutations cause this

Answer 19

adenocarcinoma

Question 20

mucin producing
gland forming cancer

Answer 20

adenocarcinoma

Question 21

Answer 21

adenocarcinoma

Question 22

___ type adenocarcinoma

Answer 22

solid type

Question 23

____ type adenocarcinoma

Answer 23

acinar stain

Question 24

____ type adenocarcinoma

Answer 24

acinar (glandular)

Question 25

____ type adenocarcinoma

Answer 25

papillary type

Question 26

Key feature is their growth pattern along preexisting structures (subtype of adenocarcinoma)

Answer 26

bronchioloalveolar carcinoma

Question 27

Answer 27

bronchioloalveolar carcinoma

Question 28

nests of neuroendocrine cells chromogranin +

Answer 28

carcinoid tumor (NSCLC)

Question 29

centrally located IHC + for chromogranin and synaptophysin

Answer 29

SCLC

Question 30

due to Rb gene mutations

Answer 30

SCLC

Question 31

Answer 31

SCLC

Question 32

Answer 32

neuroendocrine tumor (SCLC)

Question 33

paraneoplastic syndromes associated with SCLC

Answer 33

cushing syndrome SIADH anti-neuron

Question 34

most common paraneoplastic syndrome seen with SCC

Answer 34

hypercalcemia

Question 35

most common paraneoplastic syndromes with SCLC

Answer 35

cushing (ACTH) SIADH (hyponatremia)

Question 36

neoplasm of apex of the lung associated with ptosis, myosis, anhydrosis

Answer 36

Horner's Syndrome

Question 37

arise from neuroendocrine cells (Kulchitsky cells) most common in main stem bronchi

Answer 37

bronchial carcinoids

Question 38

diaphragmatic paralysis from what

Answer 38

phrenic n compression

Question 39

hoarseness from what

Answer 39

recurrent laryngeal n compression

Question 40

lung cancer pleural effusion

Answer 40

exudative

Question 41

Answer 41

rosettes seen in neuroendocrine tumors

Question 42

flushing, diarrhea, cyanosis

Answer 42

carcinoid syndrome

Question 43

rare cancer of mesothelial cells exposure to asbestos

Answer 43

mesothelioma

Question 44

cytokeratin + calretinin +

Answer 44

mesothelioma

Question 45

Answer 45

mesothelioma

Question 46

stage?

Answer 46

stage I

Question 47

stage?

Answer 47

stage II

Question 48

stage?

Answer 48

stage III

Question 49

stage?

Answer 49

stage IV