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RES Biweekly 2 > Sosnowski- Lung Cancer > Flashcards

Sosnowski- Lung Cancer Flashcards

1
Q

most lung cancer is what

A

metastatic cancer

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1
Q

____ is the number one cancer-related cause of deaths in industrialized countries

A

primary lung cancer

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2
Q
A

metastatic lung cancer

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3
Q

1 cancer in males

A

prostate

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4
Q

1 cancer in females

A

breast

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5
Q

SCC, adenocarcinoma, and carcinoid tumor are what lung cancer

A

non small cell lung cancer (NSCLC)

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6
Q

treated best with surgery

A

NSCLC

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7
Q

derived from neuroendocrine cells

A

SCLC

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8
Q

not curable by surgery due to probable metastasis at time of diagnosis

A

SCLC

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9
Q

best treated with chemo and radiation

A

SCLC

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10
Q

is NSCLC or SCLC more common

A

NSCLC

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11
Q

_____% of lung cancer occurs in active smokers and those who have stopped recently

A

90%

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12
Q

___ and ___ have strongest association w/ tobacco exposure

A

SCC and SCLC

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13
Q
A

SCC

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14
Q

pathophys includes squamous metaplasia

A

SCC

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15
Q

centrally located

A

SCC

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16
Q
A

SCC

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17
Q

stained with cytokeratin

A

SCC

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18
Q

peripherally located
most common in woman and nonsmokers

A

adenocarcinoma

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19
Q

EGFR, KRAS, and ALK activating mutations cause this

A

adenocarcinoma

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20
Q

mucin producing
gland forming cancer

A

adenocarcinoma

21
Q
A

adenocarcinoma

22
Q

___ type adenocarcinoma

A

solid type

23
Q

____ type adenocarcinoma

A

acinar stain

24
Q

____ type adenocarcinoma

A

acinar (glandular)

25
Q

____ type adenocarcinoma

A

papillary type

26
Q

Key feature is their growth pattern along preexisting structures (subtype of adenocarcinoma)

A

bronchioloalveolar carcinoma

27
Q
A

bronchioloalveolar carcinoma

28
Q

nests of neuroendocrine cells
chromogranin +

A

carcinoid tumor (NSCLC)

29
Q

centrally located
IHC + for chromogranin and synaptophysin

A

SCLC

30
Q

due to Rb gene mutations

A

SCLC

31
Q
A

SCLC

32
Q
A

neuroendocrine tumor (SCLC)

33
Q

paraneoplastic syndromes associated with SCLC

A

cushing syndrome
SIADH
anti-neuron

34
Q

most common paraneoplastic syndrome seen with SCC

A

hypercalcemia

35
Q

most common paraneoplastic syndromes with SCLC

A

cushing (ACTH)
SIADH (hyponatremia)

36
Q

neoplasm of apex of the lung
associated with ptosis, myosis, anhydrosis

A

Horner’s Syndrome

37
Q

arise from neuroendocrine cells (Kulchitsky cells)
most common in main stem bronchi

A

bronchial carcinoids

38
Q

diaphragmatic paralysis from what

A

phrenic n compression

39
Q

hoarseness from what

A

recurrent laryngeal n compression

40
Q

lung cancer pleural effusion

A

exudative

41
Q
A

rosettes seen in neuroendocrine tumors

42
Q

flushing, diarrhea, cyanosis

A

carcinoid syndrome

43
Q

rare cancer of mesothelial cells
exposure to asbestos

A

mesothelioma

44
Q

cytokeratin +
calretinin +

A

mesothelioma

45
Q
A

mesothelioma

46
Q

stage?

A

stage I

47
Q

stage?

A

stage II

48
Q

stage?

A

stage III

49
Q

stage?

A

stage IV

RES Biweekly 2 (14 decks)

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