Smooth Muscle Tumors, Vascular Tumors, Synovial Sarcoma

Question 1

What are two general types of smooth muscle tumors?

Answer 1

Leiomyomas and Leiomyosarcoma

Question 2

What differentiates a leiomyosarcoma from a leiomyoma?

Answer 2

High mitotic activity of a leiomyosarcoma

Question 3

What is a hemangioma

Answer 3

Benign vascular tumor

Question 4

What is a highly malignant soft tissue tumor that arises in the region of a joint usually in association with tendon sheaths, bursae and joint capsules?

Answer 4

Synovial sarcoma

Question 5

What genetic abnormality is displayed in synovial sarcomas?

Answer 5

Chromosomal translocation involving chromosomes X and 18

Question 6

What is the microscopic description of synovial sarcoma?

Answer 6

Biphasic pattern - Fluid-filled glandular spaces lined by epithelium-like tumor cells in a sarcomatous background

Question 7

What is a monophasic synovial sarcoma?

Answer 7

A biphasic synovial sarcoma lacking the epithelial component