Primary Hyperparathyroidism Flashcards

1
Q

What is primary hyperparathyroidism?

A

Bone resorption due to inappropriate secretion of PTH

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2
Q

What are the histiologic bone changes that occur in primary hyperthyroidism?

A

Osteitis fibrosa

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3
Q

What is the primary cause of primary hyperparathyroidism?

A

Parathyroid adenomas

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4
Q

What effect does PTH have on the kidney?

A

Increase calcium reabsorption and increase 1Alpha-Hydroxylase activity (increasing active Vit D)

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5
Q

What is a “brown tumor” associated with?

A

Endstage of primary hyperparathyroidism in which areas of fibrosis contain reactive woven bone and heosiderin-laden macrophages

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6
Q

What is the classic finding of osteitis fibrosa cystica?

A

Presence of multiple, localized, lytic lesions, which represent hemorrhagic cysts or masses of fibrous tissue

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7
Q

What are the classic clinical findings of primary hyperparathyroidism?

A

Stones, Moans, Bones, and Groans

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