Small-Vessel vasculitides - WEGNER'S GRANULOMATOSIS (Granulomatosis with polyangitis) Flashcards
1
Q
what is granulomatosis with polyangitis?
A
= blood vessels become inflamed.
2
Q
what areas does it mainly affect?
A
Affects mainly the;
- ears
- nose
- sinuses
- kidneys
- lungs
3
Q
what are the symptoms of granulomatosis with polyangitis?
A
- cough
- dyspnoea
- pleuritic chest pain
- haemoptysis
4
Q
what would imaging results show?
A
- multiple nodules
- areas of consolidation
- opacification
5
Q
how would you confirm this disease?
A
by performing biopsies
6
Q
how would you treat it?
A
1) immunosuppresant therapy with a combination of glucocorticoids and cyclophosphamide, rituximab or methotrexate
7
Q
who is most typically affected with this?
A
older adults
